P bodies: at the crossroads of post-transcriptional pathways (Q28280058)

Bringing the role of mRNA decay in the control of gene expression into focus

Europe PubMed Central

cites work

1 reference

Process or perish: quality control in mRNA biogenesis

31 March 2020

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Control of translation and mRNA degradation by miRNAs and siRNAs

31 March 2020

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A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

31 March 2020

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Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

31 March 2020

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Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay

31 March 2020

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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

31 March 2020

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Cytoplasmic foci are sites of mRNA decay in human cells

31 March 2020

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A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

31 March 2020

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The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

31 March 2020

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RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules

31 March 2020

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Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body

31 March 2020

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Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

31 March 2020

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Processing body autoantibodies reconsidered

31 March 2020

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Novel Sm-like proteins with long C-terminal tails and associated methyltransferases

31 March 2020

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Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stability

31 March 2020

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GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

31 March 2020

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Processing bodies require RNA for assembly and contain nontranslating mRNAs

31 March 2020

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Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies

31 March 2020

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Targeting of aberrant mRNAs to cytoplasmic processing bodies

31 March 2020

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A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

31 March 2020

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A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay

31 March 2020

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The enzymes and control of eukaryotic mRNA turnover

31 March 2020

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RNA-quality control by the exosome

31 March 2020

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Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae

31 March 2020

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Mutations in the Saccharomyces cerevisiae LSM1 gene that affect mRNA decapping and 3' end protection

31 March 2020

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The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p

31 March 2020

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A Sm-like protein complex that participates in mRNA degradation

31 March 2020

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Yeast Sm-like proteins function in mRNA decapping and decay

31 March 2020

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Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs

31 March 2020

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General translational repression by activators of mRNA decapping

31 March 2020

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Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

31 March 2020

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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

31 March 2020

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

31 March 2020

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Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

31 March 2020

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Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

31 March 2020

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Early nonsense: mRNA decay solves a translational problem

31 March 2020

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Computational modeling and experimental analysis of nonsense-mediated decay in yeast

31 March 2020

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An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation

31 March 2020

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Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway

31 March 2020

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Premature termination codons enhance mRNA decapping in human cells.

31 March 2020

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Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

31 March 2020

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Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

31 March 2020

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SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

31 March 2020

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SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

31 March 2020

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SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A.

31 March 2020

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Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

31 March 2020

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Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

31 March 2020

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Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs

31 March 2020

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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

31 March 2020

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MicroRNAs: genomics, biogenesis, mechanism, and function

31 March 2020

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RNAi: the nuts and bolts of the RISC machine

31 March 2020

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Novel modes of protein-RNA recognition in the RNAi pathway

31 March 2020

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Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

31 March 2020

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AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets

31 March 2020

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MicroRNAs direct rapid deadenylation of mRNA

31 March 2020

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Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

31 March 2020

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

31 March 2020

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

31 March 2020

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A role for the P-body component GW182 in microRNA function

31 March 2020

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Disruption of GW bodies impairs mammalian RNA interference

31 March 2020

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Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

31 March 2020

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Identification of novel argonaute-associated proteins

31 March 2020

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The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans

31 March 2020

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

31 March 2020

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Relief of microRNA-mediated translational repression in human cells subjected to stress

31 March 2020

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Formation of GW bodies is a consequence of microRNA genesis

31 March 2020

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The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules

31 March 2020

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31 March 2020

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Moving messages: the intracellular localization of mRNAs

31 March 2020

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Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

31 March 2020

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RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules

31 March 2020

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Requirement for P granules and meiosis for accumulation of the germline RNA helicase CGH-1.

31 March 2020

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Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes

31 March 2020

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A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans

31 March 2020

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A conserved RNA-protein complex component involved in physiological germline apoptosis regulation in C. elegans

31 March 2020

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staufen, a gene required to localize maternal RNAs in the Drosophila egg

31 March 2020

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Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes

31 March 2020

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Drosophila decapping protein 1, dDcp1, is a component of the oskar mRNP complex and directs its posterior localization in the oocyte.

31 March 2020

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Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis

31 March 2020

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The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components

31 March 2020

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Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation

31 March 2020

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Facilitation of dendritic mRNA transport by CPEB

31 March 2020

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Isolation and characterization of Staufen-containing ribonucleoprotein particles from rat brain

31 March 2020

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Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons

31 March 2020

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Xenopus Staufen is a component of a ribonucleoprotein complex containing Vg1 RNA and kinesin

31 March 2020

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AU-rich elements and associated factors: are there unifying principles?

31 March 2020

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

31 March 2020

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The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements

31 March 2020

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A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

31 March 2020

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Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

31 March 2020

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ARE-mRNA degradation requires the 5'-3' decay pathway.

31 March 2020

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Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

31 March 2020

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Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae

31 March 2020

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MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

31 March 2020

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Involvement of microRNA in AU-rich element-mediated mRNA instability

31 March 2020

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A conserved role of a DEAD box helicase in mRNA masking

31 March 2020

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The active form of Xp54 RNA helicase in translational repression is an RNA-mediated oligomer

31 March 2020

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Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex

31 March 2020

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Determinants of Rbp1p localization in specific cytoplasmic mRNA-processing foci, P-bodies.

31 March 2020

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The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs

31 March 2020

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Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae

31 March 2020

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Quantitative proteomics identifies Gemin5, a scaffolding protein involved in ribonucleoprotein assembly, as a novel partner for eukaryotic initiation factor 4E

31 March 2020

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Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies.

31 March 2020

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Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

31 March 2020

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Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

31 March 2020

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Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion

31 March 2020

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Vertebrate GLD2 poly(A) polymerases in the germline and the brain

31 March 2020

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Oskar protein interaction with Vasa represents an essential step in polar granule assembly

31 March 2020

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Drosophila tudor is essential for polar granule assembly and pole cell specification, but not for posterior patterning

31 March 2020

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A Sponge-like Structure Involved in the Association and Transport of Maternal Products during Drosophila Oogenesis

31 March 2020

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Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage

31 March 2020

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Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development

31 March 2020

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Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components

31 March 2020

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BDNF induces translocation of initiation factor 4E to mRNA granules: Evidence for a role of synaptic microfilaments and integrins

31 March 2020

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