Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice (Q37276227)

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scientific article published on 10 April 2009

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English	Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice	scientific article published on 10 April 2009

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice (English)

1 reference

Europe PubMed Central

19 August 2017

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

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based on heuristic

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object named as

Hanrui Zhang

3

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author name string

Jiyeon Yang

1

1 reference

Europe PubMed Central

19 August 2017

Yoonjung Park

2

1 reference

Europe PubMed Central

19 August 2017

Xiangbin Xu

4

1 reference

Europe PubMed Central

19 August 2017

Glen A Laine

5

1 reference

Europe PubMed Central

19 August 2017

Kevin C Dellsperger

6

1 reference

Europe PubMed Central

19 August 2017

Cuihua Zhang

7

1 reference

Europe PubMed Central

19 August 2017

publication date

10 April 2009

1 reference

Europe PubMed Central

19 August 2017

American Journal of Physiology Heart and Circulatory Physiology

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Europe PubMed Central

19 August 2017

296

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Europe PubMed Central

19 August 2017

H1850-8

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Europe PubMed Central

19 August 2017

6

1 reference

Europe PubMed Central

19 August 2017

Inflammation and endothelial dysfunction during aging: role of NF-kappaB

1 reference

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6 September 2017

siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle

1 reference

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Therapeutic regulation of endothelial dysfunction in type 2 diabetes mellitus.

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Obesity, Inflammation, and Insulin Resistance

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Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

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Insulin signaling in heart muscle: lessons from genetically engineered mouse models.

1 reference

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Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

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6 September 2017

Nuclear factor-kappaB: its role in health and disease

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A central role for JNK in obesity and insulin resistance

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Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells

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Superoxide, superoxide dismutase and ischemic injury

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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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The hormone resistin links obesity to diabetes

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

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Sodium salicylate inhibits macrophage TNF-alpha production and alters MAPK activation

1 reference

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 reference

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Proteasome inhibitors: valuable new tools for cell biologists

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6 September 2017

Disruption of IRS-2 causes type 2 diabetes in mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716110

6 September 2017

Distinct functional properties of IkappaB alpha and IkappaB beta

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14 September 2017

Regulation of NF-kappaB-dependent gene expression by the POU domain transcription factor Oct-1.

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26 June 2018

Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles

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Macrophages stimulated with IFN-gamma activate NF-kappa B and induce MCP-1 gene expression in primary human endothelial cells.

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Thymic lymphomas mediate non-MHC-restricted, TNF-dependent lysis of the murine sarcoma WEHI-164.

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26 June 2018

Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury

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Tumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) mice.

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TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injury

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Increased insulin receptor substrate 1 serine phosphorylation and stress-activated protein kinase/c-Jun N-terminal kinase activation associated with vascular insulin resistance in spontaneously hypertensive rats

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IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

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Myogenic activity in isolated subepicardial and subendocardial coronary arterioles

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https://pubmed.ncbi.nlm.nih.gov/19363130

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Salicylate inhibition of extracellular signal-regulated kinases and inducible nitric oxide synthase

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https://pubmed.ncbi.nlm.nih.gov/19363130

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Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/19363130

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Reduced contractile response to insulin and IGF-I in ventricular myocytes from genetically obese Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19363130

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Transcriptional regulation of the human GLUT4 gene promoter in diabetic transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19363130

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Preferential inhibition of lactate oxidation relative to glucose oxidation in the rat heart following diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19363130

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IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19363130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.01199.2008

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

ResearchGate publication ID

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