Origin and evolution of the cystic fibrosis transmembrane regulator protein R domain. (Q37223265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23578801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Origin and evolution of the cystic fibrosis transmembrane regulator protein R domain (English)

1 reference

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28 February 2020

main subject

transmembrane protein

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0 references

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2

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28 February 2020

author name string

Aswathy Sebastian

1

1 reference

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28 February 2020

Jianrong Wang

3

1 reference

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28 February 2020

Karen F Bernard

4

1 reference

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28 February 2020

Andrew B Conley

5

1 reference

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28 February 2020

Nael A McCarty

6

1 reference

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28 February 2020

I King Jordan

7

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

8 April 2013

1 reference

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28 February 2020

1 reference

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28 February 2020

volume

523

1 reference

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28 February 2020

issue

2

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28 February 2020

page(s)

137-146

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Proto-genes and de novo gene birth

28 February 2020

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters

6 September 2017

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NCBI Reference Sequences: current status, policy and new initiatives

6 September 2017

1 reference

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Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

6 September 2017

1 reference

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CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

6 September 2017

1 reference

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The ABC protein turned chloride channel whose failure causes cystic fibrosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates

6 September 2017

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Molecular phylogeny and divergence times of deuterostome animals

6 September 2017

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6 September 2017

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HyPhy: hypothesis testing using phylogenies

6 September 2017

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WebLogo: A Sequence Logo Generator

6 September 2017

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The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms

6 September 2017

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EMBOSS: the European Molecular Biology Open Software Suite

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

6 September 2017

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Preservation of duplicate genes by complementary, degenerative mutations

6 September 2017

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SMART, a simple modular architecture research tool: identification of signaling domains

6 September 2017

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

6 September 2017

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

6 September 2017

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The neighbor-joining method: a new method for reconstructing phylogenetic trees

6 September 2017

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Identification of the cystic fibrosis gene: chromosome walking and jumping

6 September 2017

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6 September 2017

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6 September 2017

Evolution and tinkering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Positive selection in alternatively spliced exons of human genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Alternatively and constitutively spliced exons are subject to different evolutionary forces.

26 June 2018

1 reference

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A genetic algorithm approach to detecting lineage-specific variation in selection pressure.

3 September 2018

1 reference

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Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Dibasic phosphorylation sites in the R domain of CFTR have stimulatory and inhibitory effects on channel activation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

ConSeq: the identification of functionally and structurally important residues in protein sequences.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793851

Cystic fibrosis transmembrane conductance regulator Cl- channels with R domain deletions and translocations show phosphorylation-dependent and -independent activity

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23578801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23578801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of CFTR channel gating

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23578801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.GENE.2013.02.050

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23578801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23578801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference