Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera. (Q37166443)

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scientific article published on 03 July 2013

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English	Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera.	scientific article published on 03 July 2013

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2 March 2020

Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera (English)

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Giulia Federici

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Valentina Tirelli

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Gabriella Girelli

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Lilian Varricchio

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Lilian Varricchio

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Francesca Masiello

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Francesca Masiello

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Emanuel F Petricoin

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Stefania Vaglio

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Stefania Vaglio

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Agostino Tafuri

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Todd Hricik

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Fiorella Ciaffoni

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Ross L Levine

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Anna Rita F Migliaccio

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Giuliana Alimena

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3 July 2013

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2 March 2020

American Journal of Hematology

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723-729

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Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis

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The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients

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New insights into PTEN.

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Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth

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Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia

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C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors

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Erythropoietin induces tyrosine phosphorylation of Jak2, STAT5A, and STAT5B in primary cultured human erythroid precursors.

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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

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Definition, clinical features and diagnosis of polycythaemia vera

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6 September 2017

Protein kinase C alpha controls erythropoietin receptor signaling

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Under HEMA conditions, self-replication of human erythroblasts is limited by autophagic death

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3 September 2018

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Erythropoiesis in polycythemia vera is hyper-proliferative and has accelerated maturation

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Myeloproliferative disorders

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12 December 2020

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Polycythemia vera: hormonal modulation of erythropoiesis in vitro

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https://pubmed.ncbi.nlm.nih.gov/23720412

12 December 2020

based on heuristic

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The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro

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https://pubmed.ncbi.nlm.nih.gov/23720412

12 December 2020

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10.1002/AJH.23487

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2 March 2020

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2 March 2020

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