p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria (Q37072296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Paolo Pinton

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

20 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

Cell Cycle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

304-308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

Biosensors for the detection of calcium and pH.

1 January 2020

cites work

1 reference

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29 September 2017

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Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity

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29 September 2017

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Cell death: critical control points

29 September 2017

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29 September 2017

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Mitochondrial formation of reactive oxygen species

29 September 2017

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Aging: a theory based on free radical and radiation chemistry

29 September 2017

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

29 September 2017

1 reference

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Caloric restriction, gene expression, and aging

29 September 2017

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p66(Shc): at the crossroad of oxidative stress and the genetics of aging

29 September 2017

1 reference

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Calcium signaling and apoptosis

29 September 2017

1 reference

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

29 September 2017

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29 September 2017

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

29 September 2017

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Mechanisms of aging: an appraisal of the oxidative stress hypothesis

29 September 2017

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29 September 2017

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The versatility and universality of calcium signalling

29 September 2017

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The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

29 September 2017

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29 September 2017

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29 September 2017

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

29 September 2017

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Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

29 September 2017

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The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism

27 June 2018

1 reference

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p66(shc) is highly expressed in fibroblasts from centenarians.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696632

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

27 June 2018

1 reference

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Apoptosis driven by IP(3)-linked mitochondrial calcium signals

27 June 2018

1 reference

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

27 June 2018

1 reference

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Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696632

X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates

27 June 2018

1 reference

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PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

27 June 2018

1 reference

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Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes

4 September 2018

1 reference

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The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696632

Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein.

4 September 2018

1 reference

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Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span.

4 September 2018

1 reference

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Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis.

4 September 2018

1 reference

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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

4 September 2018

1 reference

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To die or not to die: an overview of apoptosis and its role in disease.

4 September 2018

1 reference

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Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18235239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18235239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.7.3.5360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235239%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference