Phosphorylation-specific prolyl isomerization: is there an underlying theme? (Q28248256)

A human peptidyl-prolyl isomerase essential for regulation of mitosis

Europe PubMed Central

cites work

1 reference

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

21 April 2017

1 reference

Pinning down proline-directed phosphorylation signaling

21 April 2017

1 reference

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 April 2017

1 reference

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

21 April 2017

1 reference

The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery

21 April 2017

1 reference

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

21 April 2017

1 reference

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 April 2017

1 reference

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

21 April 2017

1 reference

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

21 April 2017

1 reference

Pin1 regulates the timing of mammalian primordial germ cell proliferation

21 April 2017

1 reference

Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae

21 April 2017

1 reference

Oncogenic kinase signalling

21 April 2017

1 reference

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

21 April 2017

1 reference

Structural basis for phosphoserine-proline recognition by group IV WW domains

21 April 2017

1 reference

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 April 2017

1 reference

Pin1 modulates the dephosphorylation of the RNA polymerase II C-terminal domain by yeast Fcp1.

21 April 2017

1 reference

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 April 2017

1 reference

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

NF-kappaB in cancer: from innocent bystander to major culprit

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Evidence for a NIMA-like mitotic pathway in vertebrate cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Pinning down cell signaling, cancer and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Requirement of the prolyl isomerase Pin1 for the replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Pin1 acts catalytically to promote a conformational change in Cdc25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Pin1 modulates the structure and function of human RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Regulation of Raf-1 by direct feedback phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Prevalent overexpression of prolyl isomerase Pin1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Identification and characterization of a 14 kDa human protein as a novel parvulin-like peptidyl prolyl cis/trans isomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

IGF‐1 induces Pin1 expression in promoting cell cycle S‐phase entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Critical Role of WW Domain Phosphorylation in Regulating Phosphoserine Binding Activity and Pin1 Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

The promise and perils of Wnt signaling through beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

The subcellular destinations of APC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

The evolution of diverse biological responses to DNA damage: insights from yeast and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Oxidative stress signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

APP processing is regulated by cytoplasmic phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

7 January 2021

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

7 January 2021

Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

7 January 2021

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

7 January 2021

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://api.crossref.org/works/10.1038%2FNCB0505-435

7 January 2021