KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions. (Q37065382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24294107%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions (English)

1 reference

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2 March 2020

5

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2 March 2020

Paola Costanzo

6

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2 March 2020

author name string

Angelo Lupo

1

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2 March 2020

Elena Cesaro

2

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2 March 2020

Giorgia Montano

3

1 reference

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2 March 2020

Diana Zurlo

4

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2 March 2020

publication date

1 June 2013

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2 March 2020

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2 March 2020

volume

14

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2 March 2020

issue

4

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2 March 2020

page(s)

268-278

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Genetic and epigenetic mutations affect the DNA binding capability of human ZFP57 in transient neonatal diabetes type 1.

2 March 2020

cites work

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An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence

29 September 2017

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The KRAB-ZFP/KAP1 system contributes to the early embryonic establishment of site-specific DNA methylation patterns maintained during development

29 September 2017

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The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3

29 September 2017

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Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis.

29 September 2017

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Knockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cells

29 September 2017

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In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions

29 September 2017

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A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.

29 September 2017

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PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

29 September 2017

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Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes

29 September 2017

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Functional analysis of KAP1 genomic recruitment

29 September 2017

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ZNF224: Structure and role of a multifunctional KRAB-ZFP protein

29 September 2017

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Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Kruppel-like zinc-finger protein family and WT1 protein isoforms

29 September 2017

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Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells

29 September 2017

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Intermediate phenotypes identify divergent pathways to Alzheimer's disease

29 September 2017

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Rapid sequence and expression divergence suggest selection for novel function in primate-specific KRAB-ZNF genes

29 September 2017

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PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60.

29 September 2017

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The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.

29 September 2017

1 reference

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KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading

29 September 2017

1 reference

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A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction

29 September 2017

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ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer

29 September 2017

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Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263

29 September 2017

1 reference

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The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene

29 September 2017

1 reference

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Transcription of the mitochondrial citrate carrier gene: identification of a silencer and its binding protein ZNF224.

29 September 2017

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Blinded by the Light: The Growing Complexity of p53

29 September 2017

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KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.

29 September 2017

1 reference

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Regulator of sex-limitation KRAB zinc finger proteins modulate sex-dependent and -independent liver metabolism.

29 September 2017

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A census of human transcription factors: function, expression and evolution

29 September 2017

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Adaptive evolution in zinc finger transcription factors

29 September 2017

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ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway

29 September 2017

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Differential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Krüppel-like zinc-finger protein family

29 September 2017

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Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells

29 September 2017

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The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression

29 September 2017

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Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature

29 September 2017

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A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors

29 September 2017

1 reference

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Biological and prognostic significance of chromosome 5q deletions in myeloid malignancies

29 September 2017

1 reference

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The Krüppel-like zinc-finger protein ZNF224 represses aldolase A gene transcription by interacting with the KAP-1 co-repressor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The KIR gene family: life in the fast lane of evolution

29 September 2017

1 reference

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A novel KRAB zinc-finger protein, ZNF480, expresses in human heart and activates transcriptional activities of AP-1 and SRE.

29 September 2017

1 reference

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Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif

29 September 2017

1 reference

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Zinc finger protein ZNF202 structure and function in transcriptional control of HDL metabolism

29 September 2017

1 reference

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Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression

29 September 2017

1 reference

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KRAB-containing zinc-finger repressor proteins

29 September 2017

1 reference

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Degradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage

29 September 2017

1 reference

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Transcriptional repression in eukaryotes: repressors and repression mechanisms.

29 September 2017

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Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters

29 September 2017

1 reference

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ZNF202 is inversely regulated with its target genes ABCA1 and apoE during macrophage differentiation and foam cell formation

29 September 2017

1 reference

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Structural classification of zinc fingers: survey and summary

29 September 2017

1 reference

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A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gene expression

29 September 2017

1 reference

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The control of expression of the alpha-globin gene cluster

29 September 2017

1 reference

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Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development.

29 September 2017

1 reference

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A Krüppel-associated box-zinc finger protein, NT2, represses cell-type-specific promoter activity of the alpha 2(XI) collagen gene

29 September 2017

1 reference

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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

29 September 2017

1 reference

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Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm

29 September 2017

1 reference

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Three classes of C2H2 zinc finger proteins

29 September 2017

1 reference

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All in the family: the BTB/POZ, KRAB, and SCAN domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Alternative promoter usage and splicing of ZNF74 multifinger gene produce protein isoforms with a different repressor activity and nuclear partitioning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Isolation, characterization, and mapping of a novel human KRAB zinc finger protein encoding gene ZNF463.

29 September 2017

1 reference

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Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo

29 September 2017

1 reference

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Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD

29 September 2017

1 reference

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Zinc finger proteins: new insights into structural and functional diversity

29 September 2017

1 reference

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Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

A broad role for the zinc finger protein ZNF202 in human lipid metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Odorant receptor genes in humans

29 September 2017

1 reference

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Polymorphism of the human beta3-adrenoceptor gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

KAP-1, a novel corepressor for the highly conserved KRAB repression domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Krüppel-associated boxes are potent transcriptional repression domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Trp64Arg variant of the beta3-adrenoceptor and insulin resistance in obese postmenopausal women.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Zinc fingers are sticking together

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Multifunctional proteins suggest connections between transcriptional and post-transcriptional processes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Aberrant alternative splicing of human zinc finger gene ZNF268 in human hematological malignancy.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Identification of a KRAB-containing zinc finger protein, ZNF304, by AU-motif-directed display method and initial characterization in lymphocyte activation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731817

A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24294107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High-resolution localization of 69 potential human zinc finger protein genes: A number are clustered

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24294107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A novel 19q13 nucleolar zinc finger protein suppresses tumor cell growth through inhibiting ribosome biogenesis and inducing apoptosis but is frequently silenced in multiple carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24294107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2174/13892029113149990002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24294107%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24294107%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24294107%20AND%20SRC:MED&resulttype=core&format=json