The control of expression of the alpha-globin gene cluster (Q35038968)

5 August 2017

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title

The control of expression of the alpha-globin gene cluster (English)

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5 August 2017

1

Hua-bing Zhang

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5 August 2017

De-Pei Liu

2

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PubMed ID

12512836

5 August 2017

Chih-Chuan Liang

series ordinal

3

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PubMed ID

12512836

5 August 2017

language of work or name

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1 December 2002

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International Journal of Hematology

5 August 2017

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5 August 2017

76

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5 August 2017

420-426

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5 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/bf02982807

5 August 2017

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In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction

21 January 2018

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Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes

21 January 2018

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CpG islands from the alpha-globin gene cluster increase gene expression in an integration-dependent manner.

21 January 2018

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Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice

21 January 2018

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Developmental silencing of the embryonic zeta-globin gene: concerted action of the promoter and the 3'-flanking region combined with stage-specific silencing by the transcribed segment

21 January 2018

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Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP

21 January 2018

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Sequence divergence in the 3' untranslated regions of human zeta- and alpha-globin mRNAs mediates a difference in their stabilities and contributes to efficient alpha-to-zeta gene development switching

21 January 2018

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Identification of a major positive regulatory element located 5' to the human zeta-globin gene

21 January 2018

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12 December 2020

The pattern of replication at a human telomeric region (16p13.3): its relationship to chromosome structure and gene expression

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12 December 2020

Loading of DNA-binding factors to an erythroid enhancer.

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12 December 2020

Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

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Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16

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Recombination at the human alpha-globin gene cluster: sequence features and topological constraints

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Functional gene expression domains: defining the functional unit of eukaryotic gene regulation

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Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice

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Targeted inactivation of the major positive regulatory element (HS-40) of the human alpha-globin gene locus

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12 December 2020

Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.

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Conservation of position and sequence of a novel, widely expressed gene containing the major human alpha-globin regulatory element

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12 December 2020

Replication timing of genes and middle repetitive sequences.

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12 December 2020

Transcription complex stability and chromatin dynamics in vivo.

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12 December 2020

Importance of globin gene order for correct developmental expression.

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12 December 2020

Extensive methylation of a part of the CpG island located 3.0-4.5 kbp upstream to the chicken alpha-globin gene cluster may contribute to silencing the globin genes in non-erythroid cells

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cis and trans activation of globin gene transcription in transient assays

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12 December 2020

A major positive regulatory region located far upstream of the human alpha-globin gene locus

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12 December 2020

Monosomy for the most telomeric, gene-rich region of the short arm of human chromosome 16 causes minimal phenotypic effects.

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The expression of human alpha -like globin genes in transgenic mice mediated by bacterial artificial chromosome.

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A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene

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Nuclear scaffold attachment sites in the human globin gene complexes.

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The Maf transcription factors: regulators of differentiation

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The major regulatory element upstream of the alpha-globin gene has classical and inducible enhancer activity.

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A review of the molecular genetics of the human alpha-globin gene cluster

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Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain

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Understanding alpha globin gene expression: a step towards effective gene therapy.

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Non-erythroid genes inserted on either side of human HS-40 impair the activation of its natural alpha -globin gene targets without being themselves preferentially activated

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Analysis of the human zeta-globin gene promoter in transgenic mice.

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12 December 2020

The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene

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12 December 2020

Expression and developmental control of the human alpha-globin gene cluster.

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12 December 2020

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice

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12 December 2020

Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

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12 December 2020

Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster

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12 December 2020

Derepression of human embryonic zeta-globin promoter by a locus-control region sequence

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12 December 2020

Developmental regulation of the human zeta globin gene in transgenic mice

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12 December 2020

Functional roles of in vivo footprinted DNA motifs within an alpha-globin enhancer. Erythroid lineage and developmental stage specificities

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12 December 2020

Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice

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12 December 2020

The world according to Maf

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12 December 2020

Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci

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12 December 2020

Analysis of the human alpha-globin gene cluster in transgenic mice

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12 December 2020

The relationship between chromosome structure and function at a human telomeric region

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12 December 2020

Molecular-clinical spectrum of the ATR-X syndrome

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12 December 2020

CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells

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12 December 2020

Structure and function of the zeta-globin upstream regulatory element

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12 December 2020

DNA-protein interactions in the proximal zeta-globin promoter: identification of novel CCACCC- and CCAAT-binding proteins

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12 December 2020

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

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12 December 2020

Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression

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12 December 2020

Behind the scenes of gene expression.

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12 December 2020

Looping versus linking: toward a model for long-distance gene activation

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12 December 2020

Coactivation of human alpha1- and alpha2-globin genes in single induced MEL cells containing one human alpha-globin locus

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12 December 2020

alpha-thalassemia resulting from a negative chromosomal position effect

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12 December 2020

Mouse zeta- and alpha-globin genes: embryonic survival, alpha-thalassemia, and genetic background effects.

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12 December 2020

Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster

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12 December 2020

Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere

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12 December 2020

Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments

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12 December 2020

Identifiers

DOI

10.1007/BF02982807

1 reference

5 August 2017

1 reference

PubMed ID

12512836