PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease (Q24294809)

GOA release 2020-03-11

Zinc finger protein 746

1 reference

Parkin RBR E3 ubiquitin protein ligase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Yunjong Lee

4

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Valina L. Dawson

8

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Ted M. Dawson

9

object named as

Ted M Dawson

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author name string

Joo-Ho Shin

1

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Han Seok Ko

2

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Hochul Kang

3

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Yun-Il Lee

5

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Olga Pletinkova

6

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Juan C Troconso

on focus list of Wikimedia project

7

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language of work or name

English

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publication date

4 March 2011

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published in

Cell

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volume

144

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issue

5

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page(s)

689-702

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ScienceSource

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cites work

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Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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Dopamine covalently modifies and functionally inactivates parkin

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CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

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Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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Identification of far upstream element-binding protein-1 as an authentic Parkin substrate

19 March 2017

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S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

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Loss of locus coeruleus neurons and reduced startle in parkin null mice

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Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

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27 September 2017

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27 September 2017

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27 September 2017

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Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

30 May 2018

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Allosteric effects of DNA on transcriptional regulators

29 November 2018

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PINK1 points Parkin to mitochondria

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21376232

12 December 2020

inferred from PubMed ID database lookup

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.02.010

7 January 2021

Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.02.010

7 January 2021

Gene expression analysis of in vivo fluorescent cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.02.010

7 January 2021

PINK1/Parkin direct mitochondria to autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.02.010

7 January 2021

10.1016/J.CELL.2011.02.010

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21376232

1 reference