Hypoxia-inducible factor 1: master regulator of O2 homeostasis (Q77485489)

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6 December 2019

review article

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title

Hypoxia-inducible factor 1: master regulator of O2 homeostasis (English)

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6 December 2019

1

G L Semenza

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6 December 2019

publication date

1 October 1998

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Current Opinion in Genetics & Development

6 December 2019

published in

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6 December 2019

volume

8

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6 December 2019

page(s)

588-594

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6 December 2019

issue

5

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Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene

6 December 2019

cites work

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7 January 2021

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

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7 January 2021

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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7 January 2021

Purification and characterization of hypoxia-inducible factor 1

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7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

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7 January 2021

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

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7 January 2021

Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses

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7 January 2021

Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha

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7 January 2021

Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha

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7 January 2021

The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence

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7 January 2021

The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

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7 January 2021

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

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7 January 2021

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

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7 January 2021

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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7 January 2021

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

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7 January 2021

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

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7 January 2021

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

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7 January 2021

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

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7 January 2021

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

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7 January 2021

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

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7 January 2021

Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.

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7 January 2021

Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

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7 January 2021

Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells

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7 January 2021

Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species.

1 reference

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7 January 2021

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

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7 January 2021

Role of hydrogen peroxide in hypoxia-induced erythropoietin production

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7 January 2021

Cellular respiration during hypoxia. Role of cytochrome oxidase as the oxygen sensor in hepatocytes

1 reference

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7 January 2021

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

1 reference

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7 January 2021

Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1

1 reference

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7 January 2021

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

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7 January 2021

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

1 reference

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7 January 2021

Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia

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7 January 2021

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

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7 January 2021

ARNT-deficient mice and placental differentiation

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7 January 2021

In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition

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7 January 2021

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

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7 January 2021

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

1 reference

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7 January 2021

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

1 reference

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7 January 2021

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

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7 January 2021

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

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7 January 2021

cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)

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7 January 2021

Angiogenesis by gene therapy: a new horizon for myocardial revascularization?

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7 January 2021

Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.

1 reference

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7 January 2021

Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

1 reference

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7 January 2021

Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

1 reference

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7 January 2021

Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

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7 January 2021

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

1 reference

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7 January 2021

Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6

7 January 2021

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6

7 January 2021

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6

7 January 2021

Hypoxic Regulation of Lactate Dehydrogenase A

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6

7 January 2021

10.1016/S0959-437X(98)80016-6

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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