Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma. (Q37006888)

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1 March 2020

title

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma (English)

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1 March 2020

4

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Annamaria Brioli

5

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1 March 2020

Christopher P Wardell

7

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Gareth J Morgan

10

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author name string

Martin F Kaiser

1

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1 March 2020

David C Johnson

2

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1 March 2020

Ping Wu

3

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1 March 2020

Fabio Mirabella

6

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1 March 2020

Lorenzo Melchor

8

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Faith E Davies

9

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language of work or name

English

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publication date

22 May 2013

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1 March 2020

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1 March 2020

volume

122

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page(s)

219-226

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issue

2

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Loss of SPARC in bladder cancer enhances carcinogenesis and progression

1 March 2020

cites work

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DNA methylation in multiple myeloma is weakly associated with gene transcription

29 September 2017

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LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

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29 September 2017

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DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory

29 September 2017

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29 September 2017

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Significant biological role of sp1 transactivation in multiple myeloma

29 September 2017

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Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

29 September 2017

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A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

29 September 2017

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29 September 2017

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GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response

29 September 2017

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29 September 2017

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29 September 2017

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First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial

29 September 2017

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Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

29 September 2017

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Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma

29 September 2017

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29 September 2017

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Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

29 September 2017

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RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma

29 September 2017

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29 September 2017

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29 September 2017

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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

29 September 2017

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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

29 September 2017

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Common deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice

29 September 2017

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Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

29 September 2017

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Induction of class II major histocompatibility complex expression in human multiple myeloma cells by retinoid

29 September 2017

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29 September 2017

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Prognostic significance of surface markers expressed in multiple myeloma: CD56 and other antigens

29 September 2017

1 reference

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Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3709654

Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein

29 September 2017

1 reference

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Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

29 September 2017

1 reference

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The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry

4 September 2018

1 reference

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TGFbetaR2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma.

4 September 2018

1 reference

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Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications

4 September 2018

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The absence of CD56 (NCAM) on malignant plasma cells is a hallmark of plasma cell leukemia and of a special subset of multiple myeloma

4 September 2018

1 reference

12 December 2020

Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis

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12 December 2020

Lack of CD56 expression on myeloma cells is not a marker for poor prognosis in patients treated by high-dose chemotherapy and is associated with translocation t(11;14)

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12 December 2020

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

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12 December 2020

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks

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12 December 2020

Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival

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12 December 2020

10.1182/BLOOD-2013-03-487884

Identifiers

DOI

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