A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors (Q34383712)

1 August 2017

title

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors (English)

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1 August 2017

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15

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Carolina Vicente-Dueñas

Carolina Vicente-Dueñas

1

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César Cobaleda

César Cobaleda

20

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Belen Pintado

Belén Pintado

12

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Luisa M Villar

Luisa María Villar

10

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Norma C. Gutiérrez

Norma C Gutierrez

María Begoña García Cenador

7

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María Begoña García Cenador

18

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Alberto Orfao

8

Alberto Orfao

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19

Izidore S Lossos

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1 August 2017

author name string

Isabel Romero-Camarero

2

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Inés González-Herrero

3

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1 August 2017

Esther Alonso-Escudero

4

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Fernando Abollo-Jiménez

5

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Xiaoyu Jiang

6

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Nieves Marín

9

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Ma Carmen Fernández Criado

11

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Teresa Flores

13

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Diego Alonso-López

14

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Rafael Jiménez

16

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Francisco Javier García Criado

17

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Isidro Sánchez-García

21

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1 August 2017

language of work or name

English

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publication date

17 August 2012

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1 August 2017

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1 August 2017

volume

31

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1 August 2017

issue

18

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1 August 2017

page(s)

3704-3717

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Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia

1 August 2017

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6 July 2018

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6 July 2018

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Identification of primary MAFB target genes in multiple myeloma.

6 July 2018

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6 July 2018

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The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

6 July 2018

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Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.

6 July 2018

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Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance

6 July 2018

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Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

6 July 2018

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6 July 2018

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6 July 2018

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MafB is required for islet beta cell maturation

6 July 2018

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The molecular classification of multiple myeloma

6 July 2018

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Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells

6 July 2018

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MUC1 oncoprotein stabilizes and activates estrogen receptor alpha

6 July 2018

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Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human

6 July 2018

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The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

6 July 2018

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Growth factors and antiapoptotic signaling pathways in multiple myeloma

6 July 2018

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Focus on multiple myeloma

6 July 2018

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Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma

6 July 2018

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Characterization of clonogenic multiple myeloma cells

6 July 2018

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6 July 2018

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MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth

6 July 2018

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

6 July 2018

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Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

6 July 2018

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The Hedgehog and Wnt signalling pathways in cancer

6 July 2018

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The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

MafB is an inducer of monocytic differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

Consequences of chromosomal abnormalities in tumor development.

6 July 2018

1 reference

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Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

Expression of the Ly-6E.1 (Sca-1) transgene in adult hematopoietic stem cells and the developing mouse embryo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene

6 July 2018

1 reference

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Programmed cell death: apoptosis and oncogenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

Primary Bioassay of Human Myeloma Stem Cells

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

MafA has strong cell transforming ability but is a weak transactivator

6 July 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2012.227

Cell context reveals a dual role for Maf in oncogenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2012.227

MUC1 gene polymorphism in the gastric carcinogenesis pathway.

21 January 2018

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Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.227

Biology and treatment of multiple myeloma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442275

Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.227

Getting to the stem of cancer

21 January 2018

1 reference

12 December 2020

A novel transgenic mouse model of the human multiple myeloma chromosomal translocation t(14;16)(q32;q23)

1 reference

12 December 2020

The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells

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12 December 2020

The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription

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12 December 2020

The sensitivity of CD138 immunostaining of bone marrow trephine specimens for quantifying marrow involvement in MGUS and myeloma, including samples with a low percentage of plasma cells

1 reference

12 December 2020

Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)

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12 December 2020

Significance of CD44 gene products for cancer diagnosis and disease evaluation

1 reference

12 December 2020

A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique

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12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2012.227

1 reference

1 August 2017

1 reference

1 August 2017

1 reference