Neo-ligands for innate immune receptors and the etiology of sterile inflammatory disease (Q36990599)

17 August 2017

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title

Neo-ligands for innate immune receptors and the etiology of sterile inflammatory disease (English)

1 reference

17 August 2017

1

Bruce Beutler

1 reference

PubMed ID

17979843

17 August 2017

language of work or name

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1 December 2007

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17 August 2017

Immunological Reviews

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17 August 2017

220

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17 August 2017

113-128

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Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

17 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Innate immune recognition of viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

CATERPILLERs, pyrin and hereditary immunological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The challenge of emerging and re-emerging infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Innate immune sensing and its roots: the story of endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Interferon gamma receptor deficient mice are resistant to endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Genetic Control of Leucocyte Responses to Endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The chemical structure of bacterial endotoxin in relation to bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

CD14 is required for MyD88-independent LPS signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Lipopolysaccharide activates the expression of ISG15-specific protease UBP43 via interferon regulatory factor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The nature of selection on the major histocompatibility complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Licensing of natural killer cells by host major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Self-tolerance of natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Missing self recognition and self tolerance of natural killer (NK) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

TOLERANCE TO BACTERIAL PYROGENS : I. FACTORS INFLUENCING ITS DEVELOPMENT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

TOLERANCE TO BACTERIAL PYROGENS : II. ROLE OF THE RETICULO-ENDOTHELIAL SYSTEM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Killer cell receptors: keeping pace with MHC class I evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

A structural basis of the interactions between leucine-rich repeats and protein ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

CD36 is a sensor of diacylglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

CARD15 mutations in Blau syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

NOD2 and Crohn's disease: loss or gain of function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Expression of toll-like receptor 4 and endotoxin responsiveness in mice during perinatal period.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Endotoxin-mimetic effect of antibodies against Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00577.X

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Whole genome association study of rheumatoid arthritis using 27 039 microsatellites

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Comparative studies on the toxicity of Escherichia coli lipopolysaccharide endotoxin in various animal species

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Secretion of proinflammatory cytokines and chemokines during amphotericin B exposure is mediated by coactivation of toll-like receptors 1 and 2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Shared actions of endotoxin and taxol on TNF receptors and TNF release

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Precis on forward genetics in mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Activation of autoreactive B cells by CpG dsDNA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Role of diversifying selection and gene conversion in evolution of major histocompatibility complex loci

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Rapid allelic diversification and intensified selection at antigen recognition sites of the Mhc class II DPB1 locus during hominoid evolution

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Gene-specific control of inflammation by TLR-induced chromatin modifications

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Subversion of the innate immune system by a retrovirus

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-065X.2007.00577.X

Identifiers

DOI

10.1111/J.1600-065X.2007.00577.X

1 reference

17 August 2017

1 reference

PubMed ID

17979843