AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment (Q36976172)

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scientific article published on 28 March 2016

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English	AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment	scientific article published on 28 March 2016

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scholarly article

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31 March 2020

AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment (English)

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31 March 2020

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Costas Koumenis

8

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31 March 2020

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Natalie A Daurio

1

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31 March 2020

Stephen W Tuttle

2

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31 March 2020

Andrew J Worth

3

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31 March 2020

Ethan Y Song

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31 March 2020

Julianne M Davis

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31 March 2020

Nathaniel W Snyder

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31 March 2020

Ian A Blair

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31 March 2020

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28 March 2016

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31 March 2020

Cancer Research

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31 March 2020

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31 March 2020

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31 March 2020

3295-3306

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31 March 2020

ATM couples replication stress and metabolic reprogramming during cellular senescence.

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Molecular Pathways: A Novel Approach to Targeting Hypoxia and Improving Radiotherapy Efficacy via Reduction in Oxygen Demand

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Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma

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AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling

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AMPK: a contextual oncogene or tumor suppressor?

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Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

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29 September 2017

AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.

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29 September 2017

Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness

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29 September 2017

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

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29 September 2017

SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards

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29 September 2017

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

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29 September 2017

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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29 September 2017

Understanding the Warburg effect: the metabolic requirements of cell proliferation

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

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29 September 2017

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

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29 September 2017

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

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Genes that mediate breast cancer metastasis to lung

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

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29 September 2017

High-dose tamoxifen as an enhancer of etoposide cytotoxicity. Clinical effects and in vitro assessment in p-glycoprotein expressing cell lines

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Tamoxifen modulation of cisplatin sensitivity in human malignant melanoma cells

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27 June 2018

Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications.

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27 June 2018

Inhibition of protein kinase C by tamoxifen.

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27 June 2018

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

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27 June 2018

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The association of nonalcoholic steatohepatitis and tamoxifen in patients with breast cancer.

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A phase II study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma.

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4 September 2018

Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

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4 September 2018

Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

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4 September 2018

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4 September 2018

4-Hydroxytamoxifen induces slight uncoupling of mitochondrial oxidative phosphorylation system in relation to the deleterious effects of tamoxifen

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Tamoxifen in the treatment of breast cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I and pharmacokinetic study of high dose tamoxifen and weekly cisplatin in patients with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27020861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-15-2197

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

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