The shadow of death on the MET tyrosine kinase receptor (Q36961606)

17 August 2017

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title

The shadow of death on the MET tyrosine kinase receptor (English)

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17 August 2017

Tulasne D

1

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PubMed ID

17917681

17 August 2017

Foveau B

series ordinal

2

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17 August 2017

5 October 2007

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Cell Death & Differentiation

17 August 2017

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17 August 2017

15

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17 August 2017

3

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17 August 2017

427-434

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402229

17 August 2017

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cites work

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Mechanism of met oncogene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Molecular cloning and expression of human hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Evidence for the identity of human scatter factor and human hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Scatter factor/hepatocyte growth factor is essential for liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Met provides essential signals for liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Coupling Met to specific pathways results in distinct developmental outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor/scatter factor inhibits UVB-induced apoptosis of human keratinocytes but not of keratinocyte-derived cell lines via the phosphatidylinositol 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Inhibition of JNK by HGF/SF prevents apoptosis induced by TNF-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Met acts on Mdm2 via mTOR to signal cell survival during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Identity of a tumor cytotoxic factor from human fibroblasts and hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor has potent anti-proliferative activity in various tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Apoptosis of serum-free C2.8 mouse embryo hepatocytic cells caused by hepatocyte growth factor deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The role of growth factors on renal tubular cells submitted to hypoxia and deprived of glucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor protects small airway epithelial cells from apoptosis induced by tumor necrosis factor-alpha or oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor protects cardiac myocytes against oxidative stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor (HGF) protects c-met-expressing Burkitt's lymphoma cell lines from apoptotic death induced by DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

HGF/MET signalling protects Plasmodium-infected host cells from apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Induction of apoptosis by hepatocyte growth factor/scatter factor and its augmentation by phorbol esters in Meth A cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

A fibroblast-derived tumor cytotoxic factor/F-TCF(hepatocyte growth factor/HGF) has multiple functions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Growth inhibition and induction of apoptosis by HGF in transformed rat liver epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor sensitizes human ovarian carcinoma cell lines to paclitaxel and cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor disrupts cell contact and stimulates an increase in type 3 inositol triphosphate receptor expression, intracellular calcium levels, and apoptosis of rat ovarian surface epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

HGF-mediated apoptosis via p53/bax-independent pathway activating JNK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: evidence of apoptosis in dystrophin-deficient muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor gene therapy of liver cirrhosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Amplification of apoptosis through sequential caspase cleavage of the MET tyrosine kinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Many cuts to ruin: a comprehensive update of caspase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Surviving the kiss of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Receptors that mediate cellular dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Proteolytic cleavage of epidermal growth factor receptor by caspases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Identification of proteolytic fragments from ErbB-2 that induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Met, metastasis, motility and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Scatter factors and invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Met decoys: will cancer take the bait?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Trophoblast apoptosis is inhibited by hepatocyte growth factor through the Akt and β-catenin mediated up-regulation of inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor modulates H2O2-induced mesangial cell apoptosis through induction of heme oxygenase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favouring role of hypoxia-inducible factor-1 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor induces pro-apoptotic genes in HepG2 hepatoma but not in B16-F1 melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Different point mutations in the met oncogene elicit distinct biological properties.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402229

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402229

1 reference

PubMed ID

17917681

Dimensions Publication ID

17 August 2017

0 references

1 reference

PubMed ID

17917681