Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays (Q36897569)

16 August 2017

Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays (English)

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16 August 2017

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T S Gujral

1

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16 August 2017

R L Karp

2

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16 August 2017

A Finski

3

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16 August 2017

M Chan

4

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16 August 2017

P E Schwartz

5

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16 August 2017

G MacBeath

6

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16 August 2017

P Sorger

7

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16 August 2017

language of work or name

English

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publication date

3 September 2012

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16 August 2017

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16 August 2017

32

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16 August 2017

29

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16 August 2017

3470-3476

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https://scigraph.springernature.com/pub.10.1038/onc.2012.378

16 August 2017

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Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown

29 September 2017

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Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer

29 September 2017

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Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

29 September 2017

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A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers

29 September 2017

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Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks

29 September 2017

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Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

29 September 2017

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Principles and strategies for developing network models in cancer

29 September 2017

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Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling

29 September 2017

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Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence

29 September 2017

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Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

29 September 2017

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Functional proteomics to dissect tyrosine kinase signalling pathways in cancer

29 September 2017

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Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM.

29 September 2017

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Pathway analysis of breast cancer genome-wide association study highlights three pathways and one canonical signaling cascade

29 September 2017

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Functional proteomic analysis of advanced serous ovarian cancer using reverse phase protein array: TGF-beta pathway signaling indicates response to primary chemotherapy

29 September 2017

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Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

29 September 2017

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Discovery of small molecule c-Met inhibitors: Evolution and profiles of clinical candidates

29 September 2017

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Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling

29 September 2017

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Cytokine-induced signaling networks prioritize dynamic range over signal strength

29 September 2017

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AXL is a potential target for therapeutic intervention in breast cancer progression.

29 September 2017

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MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

29 September 2017

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A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells

29 September 2017

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Reverse-phase protein microarrays: application to biomarker discovery and translational medicine.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

29 September 2017

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State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling

29 September 2017

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Bead-based microfluidic immunoassays: the next generation

29 September 2017

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Gab1 is required for cell cycle transition, cell proliferation, and transformation induced by an oncogenic met receptor.

29 September 2017

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Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases

29 September 2017

1 reference

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Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells

29 September 2017

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

29 September 2017

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Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma

29 September 2017

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Cancer genes and the pathways they control

29 September 2017

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Tissue ischemia time affects gene and protein expression patterns within minutes following surgical tumor excision

29 September 2017

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Prolinks: a database of protein functional linkages derived from coevolution

29 September 2017

1 reference

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Met, metastasis, motility and more

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Signal pathway profiling of prostate cancer using reverse phase protein arrays

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Gas6 anti-apoptotic signaling requires NF-kappa B activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

A hierarchical unsupervised growing neural network for clustering gene expression patterns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

A combined algorithm for genome-wide prediction of protein function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Immunohistochemical demonstration of androgen receptor in breast cancer and its relationship to other prognostic factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

GNCPro: navigate human genes and relationships through net-walking

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Pathway alterations during glioma progression revealed by reverse phase protein lysate arrays.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

C-Met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670968

Statistical Methods for Identifying Differentially Expressed Genes in DNA Microarrays

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22945653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.378

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference

16 August 2017

1 reference