Mitochondria and cardioprotection (Q36827897)

16 August 2017

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title

Mitochondria and cardioprotection (English)

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16 August 2017

Fabio Di Lisa

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Paolo Bernardi

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Paolo Bernardi

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author name string

Marcella Canton

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16 August 2017

Roberta Menabò

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16 August 2017

Nina Kaludercic

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16 August 2017

language of work or name

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1 December 2007

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16 August 2017

Heart Failure Reviews

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16 August 2017

12

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16 August 2017

249-260

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16 August 2017

3-4

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https://scigraph.springernature.com/pub.10.1007/s10741-007-9028-z

16 August 2017

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cites work

Myocardial contractile function during ischemia and hypoxia

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https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Amphipathic metabolites and membrane dysfunction in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

The mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Myocardial K(ATP) channels in preconditioning

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

The cellular production of hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Age-dependent increase in hydrogen peroxide production by cardiac monoamine oxidase A in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9028-Z

Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

21 January 2018

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12 December 2020

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

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12 December 2020

Mitochondrial free radical generation, oxidative stress, and aging

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12 December 2020

Postconditioning inhibits mitochondrial permeability transition

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12 December 2020

Selective targeting of an antioxidant to mitochondria

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12 December 2020

Regulation of cell death: the calcium-apoptosis link

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12 December 2020

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

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12 December 2020

Calcium gain during postischemic reperfusion. The effect of 2,4-dinitrophenol

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12 December 2020

Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice

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12 December 2020

Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

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12 December 2020

Mitochondrial pathology in cardiac failure

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12 December 2020

The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore.

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12 December 2020

Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis

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12 December 2020

Dichloroacetate stimulation of glucose oxidation improves recovery of ischemic rat hearts

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12 December 2020

Monoamine oxidase: from genes to behavior

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12 December 2020

Preconditioning: the mitochondrial connection

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12 December 2020

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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12 December 2020

Oxygen-induced enzyme release. Assessment of mitochondrial function in anoxic myocardial injury and effects of the mitochondrial uncoupling agent 2,4-dinitrophenol (DNP)

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12 December 2020

Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury

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12 December 2020

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

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12 December 2020

Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes.

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12 December 2020

Temporary contractile blockade prevents hypercontracture in anoxic-reoxygenated cardiomyocytes

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12 December 2020

Trimetazidine protects isolated rat hearts against ischemia-reperfusion injury in an experimental timing-dependent manner.

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12 December 2020

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

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12 December 2020

No ischemic preconditioning in heterozygous connexin43-deficient mice

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12 December 2020

Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart

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12 December 2020

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.

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12 December 2020

The mitochondrial permeability transition pore: its fundamental role in mediating cell death during ischaemia and reperfusion

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12 December 2020

Mitochondria: are they the seat of senescence?

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12 December 2020

Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes

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12 December 2020

The carnitine acyltransferases and their role in modulating acyl-CoA pools

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12 December 2020

A mitochondrial perspective on cell death

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12 December 2020

Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine

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12 December 2020

Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

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12 December 2020

Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts

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12 December 2020

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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12 December 2020

Role of the mitochondrial permeability transition in myocardial disease

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12 December 2020

Mitochondria and cell death. Mechanistic aspects and methodological issues

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12 December 2020

Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart

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12 December 2020

Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

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12 December 2020

Cell death: critical control points

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12 December 2020

The mechanism by which the mitochondrial ATP-sensitive K+ channel opening and H2O2 inhibit the mitochondrial permeability transition

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12 December 2020

Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole

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12 December 2020

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

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12 December 2020

Role of mitochondrial permeability transition in fetal brain damage in rats

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12 December 2020

Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia.

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12 December 2020

Mitochondrial K(ATP) channels: role in cardioprotection

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12 December 2020

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

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12 December 2020

Mitochondrial membrane permeabilization in cell death

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12 December 2020

Myocardial substrate metabolism in the normal and failing heart

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12 December 2020

Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial

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12 December 2020

Mouse models of mitochondrial dysfunction and heart failure

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12 December 2020

The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

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12 December 2020

Effects of oligomycin and acidosis on rates of ATP depletion in ischemic heart muscle

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12 December 2020

Stable transfection of UCP1 confers resistance to hypoxia/reoxygenation in a heart-derived cell line.

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12 December 2020

Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria

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12 December 2020

Superoxide radical and superoxide dismutases

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12 December 2020

The metabolical effects of L-carnitine in angina pectoris

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12 December 2020

Carnitine stimulation of glucose oxidation in the fatty acid perfused isolated working rat heart

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12 December 2020

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

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12 December 2020

An essential role of the antioxidant gene Bcl-2 in myocardial adaptation to ischemia: an insight with antisense Bcl-2 therapy

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12 December 2020

Opening mitoKATP increases superoxide generation from complex I of the electron transport chain

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12 December 2020

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

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12 December 2020

The direct physiological effects of mitoK(ATP) opening on heart mitochondria.

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12 December 2020

A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation

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12 December 2020

ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria

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12 December 2020

Mitochondria, oxidants, and aging

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12 December 2020

The mitochondrial permeability transition from in vitro artifact to disease target

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12 December 2020

Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis

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12 December 2020

Effects of CCCP-induced mitochondrial uncoupling and cyclosporin A on cell volume, cell injury and preconditioning protection of isolated rabbit cardiomyocytes

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12 December 2020

Ischaemia and the myocyte cytoskeleton: review and speculation

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12 December 2020

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

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12 December 2020

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

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12 December 2020

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12 December 2020

Premature ageing in mice expressing defective mitochondrial DNA polymerase

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12 December 2020

The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents?

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12 December 2020

The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

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12 December 2020

Inborn errors of mitochondrial fatty acid oxidation

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12 December 2020

Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning

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12 December 2020

Signal transduction of ischemic preconditioning

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12 December 2020

Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine

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12 December 2020

Lipid-membrane interactions and the pathogenesis of ischemic damage in the myocardium

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12 December 2020

Acyl coenzyme A-binding protein augments bid-induced mitochondrial damage and cell death by activating mu-calpain.

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12 December 2020

Downmodulation of mitochondrial F0F1 ATP synthase by diazoxide in cardiac myoblasts: a dual effect of the drug

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12 December 2020

Calpain and mitochondria in ischemia/reperfusion injury

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12 December 2020

Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart

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12 December 2020

Ionic basis of ischaemic cardiac injury: insights from cellular studies

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12 December 2020

Reversible ischemic inhibition of F(1)F(0)-ATPase in rat and human myocardium

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12 December 2020

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative

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12 December 2020

Metabolic therapy for heart disease: impact of trimetazidine

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12 December 2020

Bcl-2 family members and apoptosis, taken to heart

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12 December 2020

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

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12 December 2020

Mitochondrial formation of reactive oxygen species

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12 December 2020

Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion

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12 December 2020

Mitochondrial defects in cardiomyopathy and neuromuscular disease

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12 December 2020

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

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12 December 2020

Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover.

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12 December 2020

Progressively developed myocardial apoptotic cell death during late phase of reperfusion

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12 December 2020

Metabolic therapy for ischemic heart disease: the rationale for inhibition of fatty acid oxidation

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12 December 2020

Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes.

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12 December 2020

Quantitation of the effect of L-carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria.

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12 December 2020

The mitochondrial permeability transition pore and its role in cell death

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12 December 2020

Delivery of bioactive molecules to mitochondria in vivo.

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12 December 2020

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

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12 December 2020

Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane

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12 December 2020

L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation.

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12 December 2020

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

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12 December 2020

Topology of superoxide production from different sites in the mitochondrial electron transport chain

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12 December 2020

Nucleotide metabolism and cellular damage in myocardial ischemia

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12 December 2020

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

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12 December 2020

Coenzyme A and carnitine distribution in normal and ischemic hearts

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12 December 2020

Mitochondrial medicine: a metabolic perspective on the pathology of oxidative phosphorylation disorders

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12 December 2020

Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy

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12 December 2020

Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases.

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12 December 2020

Mitochondrial structure and function in acute myocardial ischemic injury

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12 December 2020

Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis

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12 December 2020

Dichloroacetate improves cardiac efficiency after ischemia independent of changes in mitochondrial proton leak

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12 December 2020

Mitochondrial function as a determinant of recovery or death in cell response to injury.

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12 December 2020

Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and postischemic myocardial injury

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12 December 2020

Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.

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12 December 2020

Structural and functional properties of adult rat heart myocytes lysed with digitonin.

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12 December 2020

Mechanisms by which mitochondria transport calcium

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12 December 2020

L-carnitine inhibits hypoglycemia-induced brain damage in the rat.

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12 December 2020

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

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12 December 2020

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

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12 December 2020

EFFECT OF CARNITINE ON THE OXIDATION OF ALPHA-OXOGLUTARATE TO SUCCINATE IN THE PRESENCE OF ACETOACETATE OR PYRUVATE

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12 December 2020

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

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12 December 2020

The role of mitochondria in the salvage and the injury of the ischemic myocardium

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12 December 2020

Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition

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12 December 2020

Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

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12 December 2020

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

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12 December 2020

Role of trimetazidine in management of ischemic cardiomyopathy

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12 December 2020

Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A

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12 December 2020

The p66shc adaptor protein controls oxidative stress response and life span in mammals

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12 December 2020

Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia

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12 December 2020

Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning

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12 December 2020

10.1007/S10741-007-9028-Z

Identifiers

DOI

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16 August 2017

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