Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia (Q36755491)

16 August 2017

Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia (English)

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16 August 2017

15

Guido Marcucci

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16 August 2017

16

Marcin Kortylewski

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16 August 2017

9

Marcin Majka

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16 August 2017

1

Qifang Zhang

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16 August 2017

12

Piotr Swiderski

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16 August 2017

4

Dayson Moreira

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16 August 2017

3

Priyanka Duttagupta

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16 August 2017

Dewan Md Sakib Hossain

2

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16 August 2017

Xingli Zhao

5

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16 August 2017

Haejung Won

6

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16 August 2017

Ralf Buettner

7

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16 August 2017

Sergey Nechaev

8

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16 August 2017

Bin Zhang

10

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16 August 2017

Qi Cai

11

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16 August 2017

Ya-Huei Kuo

13

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16 August 2017

Stephen Forman

14

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16 August 2017

language of work or name

English

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publication date

21 January 2016

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16 August 2017

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16 August 2017

127

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16 August 2017

1687-1700

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13

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4817311/fullTextXML

inferred from PubMed Central ID database lookup

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Recent advance in antigen-specific immunotherapy for acute myeloid leukemia

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Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Single cell profiling of potentiated phospho-protein networks in cancer cells.

29 September 2017

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Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

29 September 2017

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

29 September 2017

1 reference

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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

29 September 2017

1 reference

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STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Leukemic dendritic cells: potential for therapy and insights towards immune escape by leukemic blasts

29 September 2017

1 reference

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Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in T cells

29 September 2017

1 reference

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

29 September 2017

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The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.

28 June 2018

1 reference

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A critical role for Stat3 signaling in immune tolerance

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Cancer therapy using oligonucleotide-based STAT3 inhibitors: will they deliver?

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

A randomized, placebo-controlled study of the pharmacokinetics, pharmacodynamics, and tolerability of the oral JAK2 inhibitor fedratinib (SAR302503) in healthy volunteers.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

In vivo pharmacodynamic imaging of proteasome inhibition

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Distinct requirements for IFNs and STAT1 in NK cell function

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817311

Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival

4 December 2018

1 reference

12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

12 December 2020

Identification of precursors of leukemic dendritic cells differentiated from patients with acute myeloid leukemia

1 reference

12 December 2020

Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells

1 reference

12 December 2020

Cytokine upregulation of the antigen presenting function of acute myeloid leukemia cells

1 reference

12 December 2020

10.1182/BLOOD-2015-08-665604

Identifiers

DOI

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16 August 2017

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16 August 2017

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