In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors. (Q34154994)

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English	In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors.	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors. (English)

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Europe PubMed Central

31 July 2017

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toll-like receptor

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based on heuristic

inferred from title

acute myeloid leukemia

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based on heuristic

inferred from title

5

object named as

Xavier Leleu

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Klaudia Kuranda

4

object named as

Klaudia Kuranda

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Europe PubMed Central

31 July 2017

author name string

Céline Berthon

1

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Europe PubMed Central

31 July 2017

Virginie Driss

2

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Europe PubMed Central

31 July 2017

Jizhong Liu

3

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Europe PubMed Central

31 July 2017

Nathalie Jouy

6

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Europe PubMed Central

31 July 2017

Dominique Hetuin

7

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Europe PubMed Central

31 July 2017

Bruno Quesnel

8

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Europe PubMed Central

31 July 2017

language of work or name

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inferred from title

publication date

4 September 2010

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Europe PubMed Central

31 July 2017

Cancer Immunology, Immunotherapy

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Europe PubMed Central

31 July 2017

59

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Europe PubMed Central

31 July 2017

12

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Europe PubMed Central

31 July 2017

1839-1849

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Europe PubMed Central

31 July 2017

https://scigraph.springernature.com/pub.10.1007/s00262-010-0909-y

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5 July 2018

Does chemotherapy modify the immune surveillance of hematological malignancies?

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5 July 2018

PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients.

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5 July 2018

Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945474

5 July 2018

TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells

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Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta

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Toll-like receptors: lessons to learn from normal and malignant human B cells

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Interaction of human PD-L1 and B7-1.

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Immunotherapy for myeloid leukemias: current status and future directions

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5 July 2018

Inhibitory B7-family molecules in the tumour microenvironment

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5 July 2018

MicroRNA expression in cytogenetically normal acute myeloid leukemia

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Dormant tumor cells as a therapeutic target?

1 reference

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BCR-ABL mutants spread resistance to non-mutated cells through a paracrine mechanism

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5 July 2018

Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies

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5 July 2018

PD-1 and its ligands in tolerance and immunity

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Hematopoietic stem cell aging: wrinkles in stem cell potential

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945474

5 July 2018

Caspase-8 dependent apoptosis induction in malignant myeloid cells by TLR stimulation in the presence of IFN-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945474

5 July 2018

Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells

1 reference

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5 July 2018

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

1 reference

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Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia

1 reference

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The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans

1 reference

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Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia.

1 reference

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Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945474

5 July 2018

Toll-like receptors on tumor cells facilitate evasion of immune surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945474

5 July 2018

NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells.

1 reference

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In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis.

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Cytosine arabinoside induces costimulatory molecule expression in acute myeloid leukemia cells.

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Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

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Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

1 reference

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gamma-ray irradiation induces B7.1 expression in myeloid leukaemic cells.

1 reference

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Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/20814675

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A new murine aggressive leukemic model

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https://pubmed.ncbi.nlm.nih.gov/20814675

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IFN-gamma regulates the expression of B7-H1 in dermal fibroblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

12 December 2020

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Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

12 December 2020

based on heuristic

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Differential cytokine and Toll-like receptor expression in leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

12 December 2020

based on heuristic

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Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

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based on heuristic

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Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

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Effect of costimulation and the microenvironment on antigen presentation by leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814675

12 December 2020

based on heuristic

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10.1007/S00262-010-0909-Y

1 reference

Europe PubMed Central

31 July 2017

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1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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