Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity (Q40351340)

19 September 2017

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity (English)

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19 September 2017

haematopoietic system

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10

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19 September 2017

1

Marcin Kortylewski

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19 September 2017

Maciej Kujawski

2

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19 September 2017

Tianhong Wang

3

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19 September 2017

Sheng Wei

4

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19 September 2017

Shumin Zhang

5

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19 September 2017

Shari Pilon-Thomas

6

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19 September 2017

Guilian Niu

7

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19 September 2017

Heidi Kay

8

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19 September 2017

James Mulé

9

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19 September 2017

Richard Jove

11

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19 September 2017

Drew Pardoll

12

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19 September 2017

Hua Yu

13

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19 September 2017

language of work or name

English

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publication date

20 November 2005

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19 September 2017

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11

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1314-1321

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12

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https://scigraph.springernature.com/pub.10.1038/nm1325

19 September 2017

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cites work

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Does the immune system see tumors as foreign or self?

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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Regulation of T cell immunity by dendritic cells

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Tumour escape from immune surveillance through dendritic cell inactivation

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Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6.

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Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

21 January 2018

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

21 January 2018

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Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

21 January 2018

1 reference

A critical role for Stat3 signaling in immune tolerance

21 January 2018

1 reference

STAT3 is required for Flt3L-dependent dendritic cell differentiation.

21 January 2018

1 reference

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

Inducible gene targeting in mice

21 January 2018

1 reference

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

21 January 2018

1 reference

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

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21 January 2018

Inflammation and cancer

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Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

21 January 2018

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

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Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

21 January 2018

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Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

21 January 2018

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Plasmacytoid dendritic cells in immunity

21 January 2018

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Close encounters of different kinds: dendritic cells and NK cells take centre stage

21 January 2018

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Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.

21 January 2018

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Cytokines in cancer pathogenesis and cancer therapy

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Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4.

21 January 2018

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Differential tumor surveillance by natural killer (NK) and NKT cells.

21 January 2018

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Cooperation between STAT3 and c-jun suppresses Fas transcription.

21 January 2018

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Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction

21 January 2018

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Bystander elimination of antigen loss variants in established tumors

21 January 2018

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

21 January 2018

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Induced somatic inactivation of STAT3 in mice triggers the development of a fulminant form of enterocolitis

21 January 2018

1 reference

Mutational switch of an IL-6 response to an interferon-gamma-like response

21 January 2018

1 reference

The role of STATs in transcriptional control and their impact on cellular function

21 January 2018

1 reference

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

21 January 2018

1 reference

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

21 January 2018

1 reference

Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2.

21 January 2018

1 reference

Influence of SHIP on the NK Repertoire and Allogeneic Bone Marrow Transplantation

21 January 2018

1 reference

Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1325

1 reference

19 September 2017

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