Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization. (Q36692512)

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scientific article published on 17 August 2005

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English	Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.	scientific article published on 17 August 2005

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5 January 2020

Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization (English)

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Hong Chen

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Michael S Kilberg

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17 August 2005

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Journal of Biological Chemistry

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34609-34616

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5 January 2020

Involvement of microRNA in AU-rich element-mediated mRNA instability

1 reference

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Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized hi

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

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30 September 2017

Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

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Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR.

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Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

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Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR.

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An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli

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ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

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Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells

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HuR and mRNA stability

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

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