Role of the transcription factor Th-POK in CD4:CD8 lineage commitment (Q36382776)

13 August 2017

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title

Role of the transcription factor Th-POK in CD4:CD8 lineage commitment (English)

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13 August 2017

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1

Dietmar J Kappes

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13 August 2017

Xi He

2

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13 August 2017

Xiao He

series ordinal

3

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13 August 2017

publication date

1 February 2006

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13 August 2017

published in

Immunological Reviews

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13 August 2017

volume

209

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13 August 2017

page(s)

237-252

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Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

13 August 2017

cites work

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Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

21 January 2018

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Another view of the selective model of thymocyte selection.

21 January 2018

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MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

21 January 2018

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Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice

21 January 2018

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The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

21 January 2018

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Evidence for differential intracellular signaling via CD4 and CD8 molecules

21 January 2018

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The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

21 January 2018

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Lck activity controls CD4/CD8 T cell lineage commitment.

21 January 2018

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Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo.

21 January 2018

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The influence of the MAPK pathway on T cell lineage commitment

21 January 2018

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The Ras/MAPK cascade and the control of positive selection

21 January 2018

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Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

21 January 2018

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Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

21 January 2018

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Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

21 January 2018

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T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

21 January 2018

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Visualization of CD4/CD8 T cell commitment

21 January 2018

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Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells

21 January 2018

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Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

21 January 2018

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A molecular chart of thymocyte positive selection.

21 January 2018

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GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

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Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.

21 January 2018

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Critical roles for transcription factor GATA-3 in thymocyte development

21 January 2018

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TOX: an HMG box protein implicated in the regulation of thymocyte selection

21 January 2018

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TOX provides a link between calcineurin activation and CD8 lineage commitment

21 January 2018

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T cell development: bottoms-up

21 January 2018

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A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

21 January 2018

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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

21 January 2018

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Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

21 January 2018

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Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes

21 January 2018

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An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells.

21 January 2018

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Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.

21 January 2018

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Hierarchical interactions of control elements determine CD8alpha gene expression in subsets of thymocytes and peripheral T cells.

21 January 2018

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The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage

21 January 2018

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

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HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells

21 January 2018

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Regulation of lineage commitment distinct from positive selection.

21 January 2018

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Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

21 January 2018

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

21 January 2018

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Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

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Positive selection induces CD4 promoter and enhancer function.

21 January 2018

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The hcKrox gene family regulates multiple extracellular matrix genes

21 January 2018

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A novel POZ/zinc finger protein, champignon, interferes with gastrulation movements in Xenopus

21 January 2018

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Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

21 January 2018

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c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis

21 January 2018

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Flexible DNA Binding of the BTB/POZ-domain Protein FBI-1

21 January 2018

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c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

An alternative pathway for gene regulation by Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00344.X

10.1111/J.0105-2896.2006.00344.X

21 January 2018

Identifiers

DOI

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13 August 2017

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