Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss (Q36347364)

13 August 2017

Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss (English)

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13 August 2017

3

1 reference

13 August 2017

C Tackenberg

5

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author name string

J H Birnbaum

series ordinal

1

1 reference

13 August 2017

J Bali

series ordinal

2

1 reference

13 August 2017

R M Nitsch

series ordinal

4

1 reference

13 August 2017

18 June 2015

1 reference

13 August 2017

Cell Death and Disease

1 reference

13 August 2017

6

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13 August 2017

e1791

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Creative Commons Attribution 4.0 International

13 August 2017

start time

1 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4669839/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/cddis.2015.160

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cites work

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NMDA-receptor activation but not ion flux is required for amyloid-beta induced synaptic depression

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30 September 2017

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Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

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Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

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A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

30 September 2017

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Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

30 September 2017

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Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

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30 September 2017

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A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux

30 September 2017

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p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis

30 September 2017

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

30 September 2017

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

30 September 2017

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A simple method for organotypic cultures of nervous tissue

30 September 2017

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Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors

30 September 2017

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Pharmacokinetic study of memantine in healthy and renally impaired subjects

29 June 2018

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Subunit-specific NMDA receptor trafficking to synapses

29 June 2018

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Effects of transient oxygen-glucose deprivation on G-proteins and G-protein-coupled receptors in rat CA3 pyramidal cells in vitro.

29 June 2018

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Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers.

29 June 2018

1 reference

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Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

22 September 2018

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Divergent pathways mediate spine alterations and cell death induced by amyloid-beta, wild-type tau, and R406W tau.

22 September 2018

1 reference

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Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production.

22 September 2018

1 reference

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Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

Amyloid beta peptide adversely affects spine number and motility in hippocampal neurons.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

Glycine binding primes NMDA receptor internalization

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

Intracellular injections of EGTA block induction of hippocampal long-term potentiation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669839

22 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26086964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2015.160

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

1 reference