Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation (Q36288511)

13 August 2017

Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation (English)

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epidermal growth factor receptor

13 August 2017

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Kristina W Thiel

series ordinal

1

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13 August 2017

Graham Carpenter

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

27 November 2007

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Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

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13 August 2017

104

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49

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13 August 2017

19238-19243

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2148274/fullTextXML

inferred from PubMed Central ID database lookup

cites work

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

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An electrostatic engine model for autoinhibition and activation of the epidermal growth factor receptor (EGFR/ErbB) family

30 September 2017

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Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.

30 September 2017

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

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Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

30 September 2017

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The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core

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gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

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Nuclear localization of EGF receptor and its potential new role as a transcription factor

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EGF receptor residues leu(679), leu(680) mediate selective sorting of ligand-receptor complexes in early endosomal compartments

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A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes

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Human cancer cells exhibit protein kinase C-dependent c-erbB-2 transmodulation that correlates with phosphatase sensitivity and kinase activity

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor

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Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654

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Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors

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Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation

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Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase

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The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site.

30 September 2017

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All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired

29 June 2018

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Epidermal growth factor (EGF) promotes phosphorylation at threonine-654 of the EGF receptor: possible role of protein kinase C in homologous regulation of the EGF receptor

29 June 2018

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Electrostatic interactions of peptides flanking the tyrosine kinase domain in the epidermal growth factor receptor provides a model for intracellular dimerization and autophosphorylation.

29 June 2018

1 reference

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A basic peptide within the juxtamembrane region is required for EGF receptor dimerization

21 January 2018

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Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

21 January 2018

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A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor

21 January 2018

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The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase

21 January 2018

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Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148274

Heregulin-dependent Trafficking and Cleavage of ErbB-4

22 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703854104

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703854104

Structure of the membrane reconstituted transmembrane-juxtamembrane peptide EGFR(622-660) and its interaction with Ca2+/calmodulin

21 January 2018

1 reference

12 December 2020

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity

1 reference

12 December 2020

Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

1 reference

12 December 2020

Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0703854104

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13 August 2017

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13 August 2017

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