Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing. (Q36030499)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

Correction for Adaptor protein 2–mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing

31 January 2020

corrigendum / erratum

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Yogikala Prabhu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Patricia V Burgos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Christina Schindler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Ginny G Farías

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Javier G Magadán

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

publication date

2 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

2339-2351

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

Intracellular trafficking of the β-secretase and processing of amyloid precursor protein

31 January 2020

cites work

1 reference

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2 October 2017

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2 October 2017

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2 October 2017

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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

2 October 2017

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2 October 2017

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Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2

2 October 2017

1 reference

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BACE1 regulates voltage-gated sodium channels and neuronal activity

2 October 2017

1 reference

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Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

2 October 2017

1 reference

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2 October 2017

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The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site

2 October 2017

1 reference

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Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses

2 October 2017

1 reference

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Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

2 October 2017

1 reference

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GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network

2 October 2017

1 reference

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beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

2 October 2017

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The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

2 October 2017

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Structure-based design of potent and selective cell-permeable inhibitors of human beta-secretase (BACE-1).

2 October 2017

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Demonstration of BACE (beta-secretase) phosphorylation and its interaction with GGA1 in cells by fluorescence-lifetime imaging microscopy

2 October 2017

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Human BACE forms dimers and colocalizes with APP.

2 October 2017

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Beta-secretase activity increases with aging in human, monkey, and mouse brain.

2 October 2017

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The GGA proteins: adaptors on the move

2 October 2017

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2 October 2017

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GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.

2 October 2017

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The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

2 October 2017

1 reference

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Clathrin-mediated endocytosis in AP-2-depleted cells

2 October 2017

1 reference

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

2 October 2017

1 reference

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Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

2 October 2017

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

2 October 2017

1 reference

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Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

2 October 2017

1 reference

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Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression

2 October 2017

1 reference

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Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

2 October 2017

1 reference

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The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

2 October 2017

1 reference

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

2 October 2017

1 reference

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Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology

2 October 2017

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Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

2 October 2017

1 reference

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Phosphorylation regulates intracellular trafficking of beta-secretase

2 October 2017

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Regulation of APP cleavage by alpha-, beta- and gamma-secretases

2 October 2017

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Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

2 October 2017

1 reference

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

2 October 2017

1 reference

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Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

2 October 2017

1 reference

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

2 October 2017

1 reference

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

2 October 2017

1 reference

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

2 October 2017

1 reference

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PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein

2 October 2017

1 reference

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A structural explanation for the recognition of tyrosine-based endocytotic signals

2 October 2017

1 reference

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

2 October 2017

1 reference

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Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

2 October 2017

1 reference

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Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

2 October 2017

1 reference

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Evidence that production and release of amyloid beta-protein involves the endocytic pathway

2 October 2017

1 reference

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Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.

2 October 2017

1 reference

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Interaction of tyrosine-based sorting signals with clathrin-associated proteins

2 October 2017

1 reference

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Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

2 October 2017

1 reference

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Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain

2 October 2017

1 reference

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Deletion of an endosomal/lysosomal targeting signal promotes the secretion of Alzheimer's disease amyloid precursor protein (APP).

11 July 2018

1 reference

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beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

11 July 2018

1 reference

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Acidification of endocytic compartments and the intracellular pathways of ligands and receptors

11 July 2018

1 reference

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Internalization efficiency of the transferrin receptor

11 July 2018

1 reference

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

11 July 2018

1 reference

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alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation.

11 July 2018

1 reference

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Screening a series of sialyltransferases for possible BACE1 substrates.

23 September 2018

1 reference

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GGA proteins mediate the recycling pathway of memapsin 2 (BACE).

23 September 2018

1 reference

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Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1.

23 September 2018

1 reference

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Inhibition of Receptor-mediated Endocytosis Demonstrates Generation of Amyloid β-Protein at the Cell Surface

23 September 2018

1 reference

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Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Processing of beta-secretase by furin and other members of the proprotein convertase family

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374752

Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22553349

12 December 2020

inferred from PubMed ID database lookup

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22553349

12 December 2020

inferred from PubMed ID database lookup

Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22553349

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E11-11-0944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

release_gi2r4u3pcze7bbou53tol7vn7a

31 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gi2r4u3pcze7bbou53tol7vn7a

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22553349%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference