Junk DNA and the long non-coding RNA twist in cancer genetics. (Q36004601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619839%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

review article

4 references

20 October 2020

17 November 2020

8 February 2021

Junk DNA and the long non-coding RNA twist in cancer genetics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619839%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

1 reference

3 April 2019

1 reference

2 August 2019

1 reference

20 October 2020

1 reference

17 November 2020

1 reference

8 February 2021

4

1 reference

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28 February 2020

Frank J. Slack

6

1 reference

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28 February 2020

George A. Calin

7

1 reference

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28 February 2020

author name string

H Ling

1

1 reference

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28 February 2020

K Vincent

2

1 reference

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28 February 2020

M Pichler

3

1 reference

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28 February 2020

I Berindan-Neagoe

5

1 reference

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English

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publication date

26 January 2015

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28 February 2020

24 September 2015

3 references

20 October 2020

17 November 2020

8 February 2021

6 references

3 April 2019

2 August 2019

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28 February 2020

20 October 2020

17 November 2020

8 February 2021

34

1 reference

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28 February 2020

issue

39

1 reference

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28 February 2020

page(s)

5003-5011

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2014.456

28 February 2020

exact match

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Long noncoding RNAs usher in a new era in the biology of enhancers

2 October 2017

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lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.

2 October 2017

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Lessons from functional analysis of genome-wide association studies

2 October 2017

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2 October 2017

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CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

2 October 2017

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Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer

2 October 2017

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Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer

2 October 2017

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X-inactivation, imprinting, and long noncoding RNAs in health and disease

2 October 2017

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Long noncoding RNAs: cellular address codes in development and disease

2 October 2017

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Structure and function of long noncoding RNAs in epigenetic regulation

2 October 2017

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Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

2 October 2017

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Xist RNA is a potent suppressor of hematologic cancer in mice

2 October 2017

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2 October 2017

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Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

2 October 2017

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2 October 2017

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2 October 2017

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Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Comprehensive molecular characterization of human colon and rectal cancer

2 October 2017

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Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.

2 October 2017

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8q24 Cancer risk allele associated with major metastatic risk in inflammatory breast cancer

2 October 2017

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The hallmarks of cancer: a long non-coding RNA point of view.

2 October 2017

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HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.

2 October 2017

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The 8q24 gene desert: an oasis of non-coding transcriptional activity.

2 October 2017

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A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese population

2 October 2017

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Structural architecture of the human long non-coding RNA, steroid receptor RNA activator

2 October 2017

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Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution

2 October 2017

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Non-coding RNAs in human disease

2 October 2017

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Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

2 October 2017

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The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin

2 October 2017

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Molecular mechanisms of long noncoding RNAs

2 October 2017

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Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

2 October 2017

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2 October 2017

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Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters.

2 October 2017

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YY1 tethers Xist RNA to the inactive X nucleation center

2 October 2017

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Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

2 October 2017

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Long noncoding RNAs and human disease

2 October 2017

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A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

2 October 2017

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Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation

2 October 2017

1 reference

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lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements

2 October 2017

1 reference

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Expression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma

2 October 2017

1 reference

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Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

2 October 2017

1 reference

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ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS.

2 October 2017

1 reference

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Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

2 October 2017

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Long noncoding RNAs with enhancer-like function in human cells

2 October 2017

1 reference

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Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

2 October 2017

1 reference

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

2 October 2017

1 reference

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Long noncoding RNA as modular scaffold of histone modification complexes

2 October 2017

1 reference

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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

2 October 2017

1 reference

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

2 October 2017

1 reference

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Widespread transcription at neuronal activity-regulated enhancers

2 October 2017

1 reference

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Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

2 October 2017

1 reference

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The landscape of somatic copy-number alteration across human cancers

2 October 2017

1 reference

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2-D structure of the A region of Xist RNA and its implication for PRC2 association

2 October 2017

1 reference

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Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions

2 October 2017

1 reference

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Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer

2 October 2017

1 reference

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Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

2 October 2017

1 reference

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Functional enhancers at the gene-poor 8q24 cancer-linked locus.

2 October 2017

1 reference

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Regulatory roles of natural antisense transcripts

2 October 2017

1 reference

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Divergent transcription from active promoters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Multiple loci with different cancer specificities within the 8q24 gene desert

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Intersection of the RNA interference and X-inactivation pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Human Alu RNA is a modular transacting repressor of mRNA transcription during heat shock

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Multiple newly identified loci associated with prostate cancer susceptibility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Polymorphisms in the H19 gene and the risk of bladder cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The H19 non-coding RNA is essential for human tumor growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Genome-wide association study identifies novel breast cancer susceptibility loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

MicroRNA signatures in human cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Antisense transcription in the mammalian transcriptome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Genome-wide prediction and identification of cis-natural antisense transcripts in Arabidopsis thaliana

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Ultraconserved Elements in the Human Genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Transcription regulation and animal diversity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Role of histone H3 lysine 27 methylation in X inactivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Tsix, a gene antisense to Xist at the X-inactivation centre

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The Structure and Function of Chromatin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Going the distance: a current view of enhancer action

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4552604

Regulation of pri-miRNA Processing by a Long Noncoding RNA Transcribed from an Ultraconserved Region

23 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.456

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.456

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.456

The long and winding road to FDA approval of a novel prostate cancer test: our story

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.456

Association between lncrna PCGEM1 polymorphisms and prostate cancer risk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.456

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.456

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619839%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619839%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619839%20AND%20SRC:MED&resulttype=core&format=json