HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis (Q35919080)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

epidermal stem cell homeostasis

2 January 2020

main subject

1 reference

Gene Ontology release 2020-05-02

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Eric J Huang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Guangwei Wei

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Stephen Ku

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Gene K Ma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Shin'ichi Saito

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Amy A Tang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jiasheng Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Ettore Appella

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Allan Balmain

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

English

0 references

publication date

31 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

2 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

13040-13045

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

2 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

27 July 2018

1 reference

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Wnt signalling in stem cells and cancer

27 July 2018

1 reference

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Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis

27 July 2018

1 reference

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G1 cell-cycle control and cancer

27 July 2018

1 reference

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Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

27 July 2018

1 reference

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The Wnt signaling pathway in development and disease

27 July 2018

1 reference

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Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons

27 July 2018

1 reference

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WNT and beta-catenin signalling: diseases and therapies

27 July 2018

1 reference

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Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

27 July 2018

1 reference

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Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

27 July 2018

1 reference

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Socializing with the neighbors: stem cells and their niche

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Capturing and profiling adult hair follicle stem cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Defining the epithelial stem cell niche in skin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Contribution of stem cells and differentiated cells to epidermal tumours

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Stem-cell hierarchy in skin cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Genomic approaches to identification of tumour-susceptibility genes using mouse models.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

27 July 2018

1 reference

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A common human skin tumour is caused by activating mutations in beta-catenin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

27 July 2018

1 reference

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Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Induction of papillomas with a high probability of conversion to malignancy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

1 reference

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beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

21 January 2018

1 reference

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Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0703213104

Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936219

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17666529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17666529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0703213104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

0 references

release_jhofitvsgnbyvpeqepxdw75sbu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jhofitvsgnbyvpeqepxdw75sbu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17666529%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference