Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development (Q35868129)

10 August 2017

1 reference

title

Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development (English)

1 reference

G protein-coupled receptor

10 August 2017

0 references

author name string

Yarí E Marín

series ordinal

1

1 reference

PubMed ID

15322701

10 August 2017

Suzie Chen

series ordinal

2

1 reference

10 August 2017

21 August 2004

1 reference

Journal of Molecular Medicine

10 August 2017

1 reference

10 August 2017

82

1 reference

10 August 2017

735-749

1 reference

10 August 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1007/s00109-004-0566-8

10 August 2017

0 references

cites work

Expression cloning of oncogenes by retroviral transfer of cDNA libraries

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-004-0566-8

Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-004-0566-8

The biology of prothrombin.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-004-0566-8

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

1 reference

12 December 2020

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

1 reference

12 December 2020

Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity

1 reference

12 December 2020

No longer a molecular black box--new clues to apoptosis and drug resistance in melanoma

1 reference

12 December 2020

Mitotic Activity of Epidermal Melanocytes in Uv-Irradiated Mouse Skin

1 reference

12 December 2020

Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

1 reference

12 December 2020

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

1 reference

12 December 2020

Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle

1 reference

12 December 2020

Transgenic mouse models for tumors of melanocytes and retinal pigment epithelium

1 reference

12 December 2020

Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

1 reference

12 December 2020

RAFTK/Pyk2-mediated cellular signalling

1 reference

12 December 2020

Regulation of transcription factor phosphorylation by metabotropic glutamate receptor-associated signaling pathways in rat striatal neurons

1 reference

12 December 2020

Mitogenic signaling via G protein-coupled receptors

1 reference

12 December 2020

Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways

1 reference

12 December 2020

Co-expression of metabotropic glutamate receptor type 1alpha with homer-1a/Vesl-1S increases the cell surface expression of the receptor

1 reference

12 December 2020

Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

1 reference

12 December 2020

Differential regulation of cAMP-mediated gene transcription by m1 and m4 muscarinic acetylcholine receptors. Preferential coupling of m4 receptors to Gi alpha-2.

1 reference

12 December 2020

Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment

1 reference

12 December 2020

Malignant melanoma in transgenic mice.

1 reference

12 December 2020

Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression

1 reference

12 December 2020

Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development.

1 reference

12 December 2020

Aberrant rel/nfkb genes and activity in human cancer

1 reference

12 December 2020

Autocrine and paracrine signaling through neuropeptide receptors in human cancer

1 reference

12 December 2020

Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes

1 reference

12 December 2020

Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells

1 reference

12 December 2020

Wnt signalling required for expansion of neural crest and CNS progenitors.

1 reference

12 December 2020

Role and regulation of the thrombin receptor (PAR-1) in human melanoma

1 reference

12 December 2020

Mutations of the BRAF gene in human cancer

1 reference

12 December 2020

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

12 December 2020

A His19 to Ala mutant of melanoma growth-stimulating activity is a partial antagonist of the CXCR2 receptor.

1 reference

12 December 2020

Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones.

1 reference

12 December 2020

Spontaneous melanocytosis in transgenic mice

1 reference

12 December 2020

Gene regulation in melanoma progression by the AP-2 transcription factor

1 reference

12 December 2020

Cancer statistics, 2003.

1 reference

12 December 2020

Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics

1 reference

12 December 2020

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

1 reference

12 December 2020

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

1 reference

12 December 2020

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

1 reference

12 December 2020

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

1 reference

12 December 2020

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1 reference

12 December 2020

Glutamate antagonists: deadly liaisons with cancer

1 reference

12 December 2020

Development of heritable melanoma in transgenic mice.

1 reference

12 December 2020

Endothelin-1: a multifunctional molecule in cancer

1 reference

12 December 2020

High frequency of BRAF mutations in nevi

1 reference

12 December 2020

The Ca-calmodulin-dependent protein kinase cascade

1 reference

12 December 2020

Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression.

1 reference

12 December 2020

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

1 reference

12 December 2020

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

1 reference

12 December 2020

Interactions between ionotropic and metabotropic glutamate receptors regulate cAMP response element-binding protein phosphorylation in cultured striatal neurons

1 reference

12 December 2020

The regulation of normal melanocyte proliferation

1 reference

12 December 2020

Endothelin 3 promotes neural crest cell proliferation and mediates a vast increase in melanocyte number in culture

1 reference

12 December 2020

Deregulated E2F transcriptional activity in autonomously growing melanoma cells

1 reference

12 December 2020

Autocrine growth factors in human small cell lung cancer.

1 reference

12 December 2020

How MAP kinases are regulated

1 reference

12 December 2020

Opposing effects of protein kinase C and protein kinase A on metabotropic glutamate receptor signaling: selective desensitization of the inositol trisphosphate/Ca2+ pathway by phosphorylation of the receptor-G protein-coupling domain

1 reference

12 December 2020

Inhibition of PKCalpha decreases the gelatinase activity and the angiogenic and metastatic ability of the highly metastatic B16 murine melanoma cells

1 reference

12 December 2020

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

1 reference

12 December 2020

Apoptosis regulators and responses in human melanocytic and keratinocytic cells

1 reference

12 December 2020

Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection.

1 reference

12 December 2020

Agonist-induced internalization of metabotropic glutamate receptor 1A: structural determinants for protein kinase C- and G protein-coupled receptor kinase-mediated internalization

1 reference

12 December 2020

Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins

1 reference

12 December 2020

Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair

1 reference

12 December 2020

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

1 reference

12 December 2020

Molecular events in melanoma development and progression

1 reference

12 December 2020

Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases

1 reference

12 December 2020

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1 reference

12 December 2020

Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene

1 reference

12 December 2020

Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r

1 reference

12 December 2020

Glutamate and epilepsy

1 reference

12 December 2020

Group I metabotropic glutamate receptors: implications for brain diseases

1 reference

12 December 2020

Mitogen-actived protein kinase activation is an early event in melanoma progression.

1 reference

12 December 2020

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1 reference

12 December 2020

Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways

1 reference

12 December 2020

Treatment of cancer with anticoagulants: rationale in the treatment of melanoma

1 reference

12 December 2020

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation.

1 reference

12 December 2020

How do chemokine/chemokine receptor activations affect tumorigenesis?

1 reference

12 December 2020

Aberrant expression of the growth factor Wnt-5A in human malignancy

1 reference

12 December 2020

CREB and Elk-1 phosphorylation by metabotropic glutamate receptors in striatal neurons (review).

1 reference

12 December 2020

Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

1 reference

12 December 2020

Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms

1 reference

12 December 2020

Angiotensin II activation of cyclin D1-dependent kinase activity

1 reference

12 December 2020

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans

1 reference

12 December 2020

Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells

1 reference

12 December 2020

Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway

1 reference

12 December 2020

Psi 13,14 bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo

1 reference

12 December 2020

Signal characteristics of G protein-transactivated EGF receptor

1 reference

12 December 2020

The metabotropic glutamate receptors: structure and functions

1 reference

12 December 2020

Identification and characterization of an MGSA/GRO pseudogene.

1 reference

12 December 2020

Glutamate antagonists limit tumor growth

1 reference

12 December 2020

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

1 reference

12 December 2020

Genomic sequences capable of committing mouse and rat fibroblasts to adipogenesis

1 reference

12 December 2020

Treatment with coumarin to prevent or delay recurrence of malignant melanoma

1 reference

12 December 2020

Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype.

1 reference

12 December 2020

Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair

1 reference

12 December 2020

Glutamate release promotes growth of malignant gliomas

1 reference

12 December 2020

Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations

1 reference

12 December 2020

Endogenous melanin-concentrating hormone receptor SLC-1 in human melanoma SK-MEL-37 cells

1 reference

12 December 2020

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

1 reference

12 December 2020

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

1 reference

12 December 2020

Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors.

1 reference

12 December 2020

Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms

1 reference

12 December 2020

Effects of MGSA/GRO alpha on melanocyte transformation

1 reference

12 December 2020

Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter.

1 reference

12 December 2020

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

1 reference

12 December 2020

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma

1 reference

12 December 2020

Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

12 December 2020

Activation of metabotropic glutamate receptor subtype 1/protein kinase C/mitogen-activated protein kinase pathway is required for postischemic long-term potentiation in the striatum

1 reference

12 December 2020

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

12 December 2020

Commitment of mouse fibroblasts to adipocyte differentiation by DNA transfection

1 reference

12 December 2020

Induction of cyclin D1 by simian virus 40 small tumor antigen

1 reference

12 December 2020

CREB and its associated proteins act as survival factors for human melanoma cells

1 reference

12 December 2020

Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro

1 reference

12 December 2020

Pharmacology and functions of metabotropic glutamate receptors

1 reference

12 December 2020

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

1 reference

12 December 2020

Regulation of cell proliferation by G proteins

1 reference

12 December 2020

Development of early melanocytic lesions in transgenic mice predisposed to melanoma

1 reference

12 December 2020

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

1 reference

12 December 2020

Cyclin D1 is a candidate oncogene in cutaneous melanoma

1 reference

12 December 2020

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

1 reference

12 December 2020

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

1 reference

12 December 2020

Enhanced degradation of I-kappaB alpha contributes to endogenous activation of NF-kappaB in Hs294T melanoma cells

1 reference

12 December 2020

G protein-coupled receptor kinase-mediated desensitization of metabotropic glutamate receptor 1A protects against cell death

1 reference

12 December 2020

G-protein-coupled receptors and signaling networks: emerging paradigms.

1 reference

12 December 2020

Missing pieces in the NF-kappaB puzzle

1 reference

12 December 2020

Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors.

1 reference

12 December 2020

Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

1 reference

12 December 2020

Glutamate receptor function in learning and memory

1 reference

12 December 2020

Development of cutaneous amelanotic melanoma in the absence of a functional tyrosinase

1 reference

12 December 2020

Homer 1b regulates the trafficking of group I metabotropic glutamate receptors

1 reference

12 December 2020

c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype

1 reference

12 December 2020

In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein.

1 reference

12 December 2020

Production of neuromedin B and neuromedin B gene expression in human lung tumor cell lines

1 reference

12 December 2020

An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

1 reference

12 December 2020

Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.

1 reference

12 December 2020

10.1007/S00109-004-0566-8

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15322701