Aberrant rel/nfkb genes and activity in human cancer (Q28140722)

High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro

Europe PubMed Central

title

Aberrant rel/nfkb genes and activity in human cancer (English)

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author name string

B Rayet

series ordinal

1

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C Gélinas

series ordinal

2

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language of work or name

English

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publication date

22 November 1999

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published in

Oncogene

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volume

18

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page(s)

6938-47

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issue

49

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cites work

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7 January 2021

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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Control of apoptosis by Rel/NF-kappaB transcription factors

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7 January 2021

c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition

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7 January 2021

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

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7 January 2021

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

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7 January 2021

The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines

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7 January 2021

Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo

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7 January 2021

Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

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7 January 2021

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

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7 January 2021

Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

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7 January 2021

Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein

1 reference

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7 January 2021

Rearranged NFKB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators

1 reference

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7 January 2021

Mapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein

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7 January 2021

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views

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7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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7 January 2021

Constitutive expression of lymphoma-associated NFKB-2/Lyt-10 proteins is tumorigenic in murine fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

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7 January 2021

Regulation of NF-kappaB activity by I kappaB-related proteins in adenocarcinoma cells

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7 January 2021

Regulation of major histocompatibility complex class I expression by NF-kappaB-related proteins in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

The avian transcription factor c-Rel is induced and translocates into the nucleus of thymocytes undergoing apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Characterization of a novel promoter insertion in the c-rel locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

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7 January 2021

Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Phenotypic and genotypic characterization of Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKBI) inhibitor of NF-kappa B to 4q24 and 14q13, respectively

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Bcl-3-mediated nuclear regulation of the NF-kappa B trans-activating factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

A novel NF-kappa B p65 spliced transcript lacking exons 6 and 7 in a non-small cell lung carcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

t(14;19)/BCL3 rearrangements in lymphoproliferative disorders: a review of 23 cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

BCL3 rearrangement and t(14;19)(q32;q13) in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

PRAD1/cyclin D1 proto-oncogene: genomic organization, 5' DNA sequence, and sequence of a tumor-specific rearrangement breakpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Identification of a naturally occurring transforming variant of the p65 subunit of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Loss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-Rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Structure, regulation and function of NF-kappa B

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Identification of a tumor-associated mutant form of the NF-kappaB RelA gene with reduced DNA-binding and transactivating activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

c-Rel is essential for B lymphocyte survival and cell cycle progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Alterations in NFkappaB activation in T lymphocytes of patients with renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

A new characteristic karyotypic anomaly in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkappaB p65 protein expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaB

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

NF-κB-mediated Induction ofmdr1bExpression by Insulin in Rat Hepatoma Cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation and transcriptional activation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203221

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203221

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1860898

1015500911

0 references

1860898

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference