A novel 3D high-content assay identifies compounds that prevent fibroblast invasion into tissue surrogates (Q35811284)

10 August 2017

A novel 3D high-content assay identifies compounds that prevent fibroblast invasion into tissue surrogates (English)

1 reference

10 August 2017

2

Saskia Otto

1 reference

10 August 2017

Carsten Wenzel

1

1 reference

10 August 2017

Stefan Prechtl

series ordinal

3

1 reference

10 August 2017

Karsten Parczyk

series ordinal

4

1 reference

10 August 2017

Patrick Steigemann

series ordinal

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

13 October 2015

1 reference

Experimental Cell Research

10 August 2017

1 reference

10 August 2017

339

1 reference

10 August 2017

1

1 reference

10 August 2017

35-43

1 reference

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

10 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Cancer associated fibroblasts in cancer pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

7 January 2021

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Pulmonary fibrosis: patterns and perpetrators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Molecular targets in pulmonary fibrosis: the myofibroblast in focus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Phenotypic screening in cancer drug discovery - past, present and future

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Acute lung injury fibroblast migration and invasion of a fibrin matrix is mediated by CD44.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Integrin alpha4beta1 regulates migration across basement membranes by lung fibroblasts: a role for phosphatase and tensin homologue deleted on chromosome 10

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Multiplex profiling of cellular invasion in 3D cell culture models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Spheroid-based drug screen: considerations and practical approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Novel 3D co-culture model for epithelial-stromal cells interaction in prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Three-dimensional in vitro co-culture model of breast tumor using magnetic levitation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Three-dimensional tissue culture models in cancer biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Fasudil, a Rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Long-term treatment with fasudil improves bleomycin-induced pulmonary fibrosis and pulmonary hypertension via inhibition of Smad2/3 phosphorylation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Organoid models of human and mouse ductal pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Prostaglandin E receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Prostanoid receptors: structures, properties, and functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Comparison of the actions of U-46619, a prostaglandin H2-analogue, with those of prostaglandin H2 and thromboxane A2 on some isolated smooth muscle preparations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Structure-activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Novel analytic criteria and effective plate designs for quality control in genome-scale RNAi screens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Losartan attenuates bleomycin induced lung fibrosis by increasing prostaglandin E2 synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

Mechanisms of force generation and transmission by myofibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.003

10.1016/J.YEXCR.2015.10.003

7 January 2021

Identifiers

DOI

1 reference

10 August 2017

1 reference