Accumulation of amyloid-like Aβ1-42 in AEL (autophagy-endosomal-lysosomal) vesicles: potential implications for plaque biogenesis (Q35233549)

7 August 2017

Accumulation of amyloid-like Aβ1-42 in AEL (autophagy-endosomal-lysosomal) vesicles: potential implications for plaque biogenesis (English)

1 reference

7 August 2017

0 references

Daijun Ling

1

1 reference

7 August 2017

Martha Magallanes

series ordinal

2

1 reference

7 August 2017

Paul M Salvaterra

series ordinal

3

1 reference

7 August 2017

12 March 2014

1 reference

7 August 2017

1 reference

7 August 2017

6

1 reference

7 August 2017

2

1 reference

describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4379859/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Lysosomal fusion dysfunction as a unifying hypothesis for Alzheimer's disease pathology

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Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment

13 July 2018

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Deconvolution of the confounding variations for reverse transcription quantitative real-time polymerase chain reaction by separate analysis of biological replicate data

13 July 2018

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Trafficking and proteolytic processing of APP

13 July 2018

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SASqPCR: robust and rapid analysis of RT-qPCR data in SAS

13 July 2018

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

13 July 2018

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Robust RT-qPCR data normalization: validation and selection of internal reference genes during post-experimental data analysis

13 July 2018

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Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease

13 July 2018

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Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the International Society of Amyloidosis

13 July 2018

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Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles

13 July 2018

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Macroautophagy is not directly involved in the metabolism of amyloid precursor protein

13 July 2018

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Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

13 July 2018

1 reference

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Neuropathology of Alzheimer's disease

13 July 2018

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Alzheimer's disease: insights from Drosophila melanogaster models

13 July 2018

1 reference

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Transgenic Drosophila models of Alzheimer's disease and tauopathies

13 July 2018

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

13 July 2018

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An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation

13 July 2018

1 reference

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Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila

13 July 2018

1 reference

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

13 July 2018

1 reference

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Mechanisms of amyloid plaque pathogenesis

13 July 2018

1 reference

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Intracellular amyloid-beta in Alzheimer's disease

13 July 2018

1 reference

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Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration

13 July 2018

1 reference

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Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

13 July 2018

1 reference

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Maturation of autophagic vacuoles in Mammalian cells

13 July 2018

1 reference

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Autophagy and aging: the importance of maintaining "clean" cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease

13 July 2018

1 reference

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Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

13 July 2018

1 reference

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Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases

13 July 2018

1 reference

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Role and regulation of starvation-induced autophagy in the Drosophila fat body

13 July 2018

1 reference

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Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

13 July 2018

1 reference

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Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease

13 July 2018

1 reference

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Alzheimer beta-amyloid peptides: normal and abnormal localization

13 July 2018

1 reference

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Acidic pH promotes the formation of toxic fibrils from beta-amyloid peptide

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Intraneuronal Abeta42 accumulation in human brain.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

The autophagic and endocytic pathways converge at the nascent autophagic vacuoles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Reexamination of granulovacuolar degeneration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Age-associated inclusions in normal and transgenic mouse brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Aβ secretion and plaque formation depend on autophagy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Aβ internalization by neurons and glia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Brain aging and Aβ₁₋₄₂ neurotoxicity converge via deterioration in autophagy-lysosomal system: a conditional Drosophila model linking Alzheimer's neurodegeneration with aging

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Autophagy: a broad role in unconventional protein secretion?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

The cell-selective neurotoxicity of the Alzheimer's Abeta peptide is determined by surface phosphatidylserine and cytosolic ATP levels. Membrane binding is required for Abeta toxicity.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

The use of formic acid to embellish amyloid plaque detection in Alzheimer's disease tissues misguides key observations

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Beta-amyloid plaques: stages in life history or independent origin?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379859

Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24521233

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/AN20130044

1 reference

7 August 2017

1 reference

7 August 2017

1 reference