The RAG2 C terminus suppresses genomic instability and lymphomagenesis (Q35216006)

7 August 2017

The RAG2 C terminus suppresses genomic instability and lymphomagenesis (English)

1 reference

7 August 2017

Ludovic Deriano

1

1 reference

7 August 2017

Julie Chaumeil

2

1 reference

7 August 2017

Marc Coussens

3

1 reference

7 August 2017

Asha Multani

4

1 reference

7 August 2017

YiFan Chou

5

1 reference

7 August 2017

Alexander V Alekseyenko

6

1 reference

7 August 2017

Sandy Chang

7

1 reference

7 August 2017

Jane A Skok

8

1 reference

7 August 2017

David B Roth

9

1 reference

7 August 2017

language of work or name

English

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publication date

1 March 2011

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7 August 2017

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7 August 2017

471

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7 August 2017

7336

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7 August 2017

119-123

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https://scigraph.springernature.com/pub.10.1038/nature09755

7 August 2017

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cites work

ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification

1 reference

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Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

The roles of the RAG1 and RAG2 "non-core" regions in V(D)J recombination and lymphocyte development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

RAG2's non-core domain contributes to the ordered regulation of V(D)J recombination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Methods for studying the cellular response to DNA damage: influence of the Mre11 complex on chromosome metabolism.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Circular binary segmentation for the analysis of array-based DNA copy number data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

High-resolution characterization of the pancreatic adenocarcinoma genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Mechanisms of chromosomal translocations in B cell lymphomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Atm-deficient mice: a paradigm of ataxia telangiectasia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Tumor spectrum analysis in p53-mutant mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Chromosome banding techniques

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174233

An immunoglobulin heavy-chain gene is altered in two T-cell clones

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09755

Rag mutations reveal robust alternative end joining

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09755

21 January 2018

12 December 2020

Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice

1 reference

PubMed

12 December 2020

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

1 reference

PubMed

12 December 2020

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/NATURE09755

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference