The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development (Q40689893)

22 September 2017

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development (English)

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22 September 2017

5

Garnett Kelsoe

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22 September 2017

Hong-Erh Liang

1

1 reference

22 September 2017

Lih-Yun Hsu

2

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22 September 2017

Dragana Cado

3

1 reference

22 September 2017

Lindsay G Cowell

4

1 reference

22 September 2017

Mark S Schlissel

6

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22 September 2017

language of work or name

English

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publication date

1 November 2002

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22 September 2017

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22 September 2017

17

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22 September 2017

639-651

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22 September 2017

5

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Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

V(D)J recombinase activity in a subset of germinal center B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Factors and forces controlling V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Regions of RAG1 protein critical for V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

ClpX and MuB interact with overlapping regions of Mu transposase: implications for control of the transposition pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

A role for histone acetylation in the developmental regulation of VDJ recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Mice with a fluorescent marker for interleukin 2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Complementation of V(D)J recombination deficiency in RAG-1(-/-) B cells reveals a requirement for novel elements in the N-terminus of RAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

The interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Pleiotropic changes controlled by the pre-T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

Unequal VH gene rearrangement frequency within the large VH7183 gene family is not due to recombination signal sequence variation, and mapping of the genes shows a bias of rearrangement based on chromosomal location

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900448-X

7 January 2021

10.1016/S1074-7613(02)00448-X

Identifiers

DOI

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22 September 2017

1 reference