Investigating hypoxic tumor physiology through gene expression patterns (Q35208837)

7 August 2017

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title

Investigating hypoxic tumor physiology through gene expression patterns (English)

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7 August 2017

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6

Russ Altman

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7 August 2017

7

Amato J Giaccia

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7 August 2017

Nicholas C Denko

1

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7 August 2017

Lucrezia A Fontana

2

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7 August 2017

Karen M Hudson

3

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7 August 2017

Patrick D Sutphin

4

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7 August 2017

Soumya Raychaudhuri

5

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

22

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7 August 2017

5907-5914

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7 August 2017

37

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206703

7 August 2017

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cites work

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

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Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly

21 January 2018

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Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

21 January 2018

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Functional versatility in the CRP-FNR superfamily of transcription factors: FNR and FLP.

21 January 2018

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1.

21 January 2018

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Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition

21 January 2018

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Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway

21 January 2018

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Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia

21 January 2018

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Endothelial response to hypoxia: physiologic adaptation and pathologic dysfunction

21 January 2018

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Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells

21 January 2018

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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Hypoxia regulates osteoblast gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Hypoxia-associated induction of early growth response-1 gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 January 2018

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7 January 2021

Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Von Hippel-Lindau Syndrome

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Regulation of ionic conductances and gene expression by hypoxia in an oxygen sensitive cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Exposure of cultured primary rat astrocytes to hypoxia results in intracellular glucose depletion and induction of glycolytic enzymes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206703

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206703

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7 August 2017

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