HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme (Q35170396)

6 August 2017

HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme (English)

1 reference

6 August 2017

1

1 reference

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10 June 2020

Robert Ivánek

5

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10 June 2020

Vincent M. Christoffels

10

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10 June 2020

Axel Visel

11

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10 June 2020

Javier Lopez-Rios

12

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10 June 2020

Rolf Zeller

13

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10 June 2020

author name string

Dario Speziale

2

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10 June 2020

Malak Shoukry

3

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10 June 2020

Rajiv Mohan

4

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10 June 2020

Manuel Kohler

6

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10 June 2020

Christian Beisel

7

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10 June 2020

Xiaohui Wen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453830%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Suzie J Scales

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453830%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

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publication date

10 November 2014

1 reference

6 August 2017

13

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inferred from page(s)

published in

Developmental Cell

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10 June 2020

volume

31

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10 June 2020

issue

3

1 reference

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10 June 2020

page(s)

345-357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453830%20AND%20SRC:MED&resulttype=core&format=json

Development of five digits is controlled by a bipartite long-range cis-regulator

10 June 2020

cites work

1 reference

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GATA6 is a crucial regulator of Shh in the limb bud

13 July 2018

1 reference

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Fine tuning of craniofacial morphology by distant-acting enhancers

13 July 2018

1 reference

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Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.

13 July 2018

1 reference

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Transcription factors: from enhancer binding to developmental control

13 July 2018

1 reference

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Human limb abnormalities caused by disruption of hedgehog signaling

13 July 2018

1 reference

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GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis

13 July 2018

1 reference

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Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb

13 July 2018

1 reference

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Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly

13 July 2018

1 reference

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Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis

13 July 2018

1 reference

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Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation.

13 July 2018

1 reference

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Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Dual RMCE for efficient re-engineering of mouse mutant alleles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Vertebrate limb bud development: moving towards integrative analysis of organogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Gene expression profiling of the forming atrioventricular node using a novel tbx3-based node-specific transgenic reporter

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2

13 July 2018

1 reference

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A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

13 July 2018

1 reference

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Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning

13 July 2018

1 reference

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Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud

13 July 2018

1 reference

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Network motifs: theory and experimental approaches

13 July 2018

1 reference

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VISTA Enhancer Browser--a database of tissue-specific human enhancers

13 July 2018

1 reference

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Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression

13 July 2018

1 reference

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Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

13 July 2018

1 reference

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

13 July 2018

1 reference

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Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

13 July 2018

1 reference

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A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

13 July 2018

1 reference

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Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

13 July 2018

1 reference

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A re-examination of proximodistal patterning during vertebrate limb development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Evolution of mouse T-box genes by tandem duplication and cluster dispersion.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

HoxB6-Cre transgenic mice express Cre recombinase in extra-embryonic mesoderm, in lateral plate and limb mesoderm and at the midbrain/hindbrain junction.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357275

The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25453830

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.DEVCEL.2014.09.018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453830%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453830%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference