Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis (Q35170119)

6 August 2017

Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis (English)

1 reference

6 August 2017

1 reference

3

Dorothy E Vatner

1 reference

6 August 2017

4

Stephen F Vatner

1 reference

6 August 2017

Grace J Lee

1

1 reference

PubMed ID

25600225

6 August 2017

Lin Yan

series ordinal

2

1 reference

6 August 2017

20 January 2015

1 reference

Basic Research in Cardiology

6 August 2017

1 reference

6 August 2017

110

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6 August 2017

2

1 reference

6 August 2017

7

1 reference

https://scigraph.springernature.com/pub.10.1007/s00395-015-0461-1

6 August 2017

0 references

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Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL

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Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.

13 July 2018

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Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway

13 July 2018

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Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload

13 July 2018

1 reference

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Molecular mechanisms that differentiate apoptosis from programmed necrosis

13 July 2018

1 reference

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Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase

13 July 2018

1 reference

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Regulation of the inflammatory response in cardiac repair

13 July 2018

1 reference

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Programmed necrosis, not apoptosis, in the heart

13 July 2018

1 reference

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Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

13 July 2018

1 reference

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{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways

13 July 2018

1 reference

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Cellular and molecular pathways to myocardial necrosis and replacement fibrosis

13 July 2018

1 reference

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Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences.

13 July 2018

1 reference

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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

13 July 2018

1 reference

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Apoptosis predominates in nonmyocytes in heart failure

13 July 2018

1 reference

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How dying cells alert the immune system to danger

13 July 2018

1 reference

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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

13 July 2018

1 reference

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Evans blue staining of cardiomyocytes induced by myocardial contrast echocardiography in rats: evidence for necrosis instead of apoptosis

13 July 2018

1 reference

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

13 July 2018

1 reference

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Mammalian Sterile20-like kinase 1 and the regulation of apoptosis

13 July 2018

1 reference

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Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction.

13 July 2018

1 reference

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Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?

13 July 2018

1 reference

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

13 July 2018

1 reference

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Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy

13 July 2018

1 reference

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

13 July 2018

1 reference

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MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Hyperplasia of myocyte nuclei in long-term cardiac hypertrophy in rats

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats

13 July 2018

1 reference

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Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis

13 July 2018

1 reference

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Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade.

13 July 2018

1 reference

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Paracrine effects of hypoxic fibroblast-derived factors on the MPT-ROS threshold and viability of adult rat cardiac myocytes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Attenuates Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

The time course of cardiac NF-kappaB activation and TNF-alpha secretion by cardiac myocytes after burn injury: contribution to burn-related cardiac contractile dysfunction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4357177

Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00395-015-0461-1

Colocalization of myocardial fibrosis and inflammatory cells in rats

21 January 2018

1 reference

12 December 2020

Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction

1 reference

12 December 2020

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction

1 reference

12 December 2020

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

1 reference

12 December 2020

Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats

1 reference

12 December 2020

Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis

1 reference

12 December 2020

Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury

1 reference

12 December 2020

Serum from patients with severe heart failure downregulates eNOS and is proapoptotic: role of tumor necrosis factor-alpha

1 reference

12 December 2020

Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis

1 reference

12 December 2020

Isoproterenol-induced myocardial necrosis and membrane permeability alterations in the isolated perfused rabbit heart

1 reference

12 December 2020

Adverse effects of chronic endogenous sympathetic drive induced by cardiac GS alpha overexpression

1 reference

12 December 2020

10.1007/S00395-015-0461-1

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

25600225