Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy (Q34997854)

5 August 2017

Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy (English)

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5 August 2017

dilated cardiomyopathy

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13

Dorothy E Vatner

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5 August 2017

14

Stephen F Vatner

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5 August 2017

Shimako Yamamoto

1

1 reference

5 August 2017

Guiping Yang

2

1 reference

5 August 2017

Daniela Zablocki

3

1 reference

5 August 2017

Jing Liu

4

1 reference

5 August 2017

Chull Hong

5

1 reference

5 August 2017

Song-Jung Kim

6

1 reference

5 August 2017

Sandra Soler

7

1 reference

5 August 2017

Mari Odashima

8

1 reference

5 August 2017

Jill Thaisz

9

1 reference

5 August 2017

Ghassan Yehia

10

1 reference

5 August 2017

Carlos A Molina

11

1 reference

5 August 2017

Atsuko Yatani

12

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5 August 2017

Junichi Sadoshima

15

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5 August 2017

language of work or name

English

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publication date

1 May 2003

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Journal of Clinical Investigation

5 August 2017

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5 August 2017

111

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5 August 2017

1463-1474

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5 August 2017

10

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Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Identification of a novel Ras-regulated proapoptotic pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Molecular mechanisms of apoptosis in the cardiac myocyte

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

The role of apoptosis in myocardial ischemia: a critical appraisal

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Evidence that human cardiac myocytes divide after myocardial infarction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

The Ste20 group kinases as regulators of MAP kinase cascades

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Activation of a 36-kD MBP kinase, an active proteolytic fragment of MST/Krs proteins, during anticancer drug-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Ischemic preconditioning reduces apoptosis by upregulating anti-death gene Bcl-2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Postmitochondrial regulation of apoptosis during heart failure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Differential regulation of inotropy and lusitropy in overexpressed Gsalpha myocytes through cAMP and Ca2+ channel pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Signaling by the germinal center kinase family of protein kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Phospholamban deficiency alters inactivation kinetics of L-type Ca2+ channels in mouse ventricular myocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Newly identified stress-responsive protein kinases, Krs-1 and Krs-2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Reperfusion injury induces apoptosis in rabbit cardiomyocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Cloning and characterization of a human protein kinase with homology to Ste20

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=155047

Myocyte death in the pathological heart

26 October 2018

1 reference

12 December 2020

Apoptosis is initiated by myocardial ischemia and executed during reperfusion

1 reference

12 December 2020

Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation

1 reference

12 December 2020

Involvement of CD95/Apo1/Fas in Cell Death After Myocardial Ischemia

1 reference

12 December 2020

MST1-JNK promotes apoptosis via caspase-dependent and independent pathways

1 reference

12 December 2020

Cyclosporine reduces left ventricular mass with chronic aortic banding in mice, which could be due to apoptosis and fibrosis

1 reference

12 December 2020

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

12 December 2020

Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats

1 reference

12 December 2020

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes

1 reference

12 December 2020

Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling

1 reference

12 December 2020

Apoptosis in human acute myocardial infarction

1 reference

12 December 2020

Apoptosis in the failing human heart

1 reference

12 December 2020

Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation

1 reference

12 December 2020

Co-localization of the cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat

1 reference

12 December 2020

Apoptosis of cardiac myocytes in Gsalpha transgenic mice

1 reference

12 December 2020

The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI17459

1 reference

5 August 2017

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5 August 2017

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