The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function (Q35126979)

6 August 2017

The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function (English)

1 reference

6 August 2017

Brandon Scott Carpenter

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Renee L Barry

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Kristen J Verhey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Benjamin L Allen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

14 January 2015

1 reference

6 August 2017

Journal of Cell Science

1 reference

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31 May 2020

volume

128

1 reference

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31 May 2020

issue

5

1 reference

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31 May 2020

page(s)

1034-1050

1 reference

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describes a project that uses

31 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4342584/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

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Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo

28 July 2018

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POPX2 phosphatase regulates the KIF3 kinesin motor complex

28 July 2018

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Intraflagellar transport complex structure and cargo interactions

28 July 2018

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Kinesin-2: a family of heterotrimeric and homodimeric motors with diverse intracellular transport functions

28 July 2018

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Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction

28 July 2018

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28 July 2018

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IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport

28 July 2018

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Hedgehog signaling and the Gli code in stem cells, cancer, and metastases

28 July 2018

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Kinesin-3 KLP-6 regulates intraflagellar transport in male-specific cilia of Caenorhabditis elegans

28 July 2018

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The retrograde IFT machinery of C. elegans cilia: two IFT dynein complexes?

28 July 2018

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Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function

28 July 2018

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Regulation of mammalian Gli proteins by Costal 2 and PKA in Drosophila reveals Hedgehog pathway conservation

28 July 2018

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Complex interactions between genes controlling trafficking in primary cilia

28 July 2018

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Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

28 July 2018

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A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes

28 July 2018

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Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

28 July 2018

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The primary cilium: a signalling centre during vertebrate development

28 July 2018

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Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

28 July 2018

1 reference

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Intraflagellar transport: it's not just for cilia anymore

28 July 2018

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Kinesin superfamily motor proteins and intracellular transport

28 July 2018

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Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling

28 July 2018

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The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development

28 July 2018

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The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling

28 July 2018

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Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

28 July 2018

1 reference

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Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.

28 July 2018

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Protein phosphatase Dusp26 associates with KIF3 motor and promotes N-cadherin-mediated cell-cell adhesion

28 July 2018

1 reference

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The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development

28 July 2018

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Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

28 July 2018

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Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

28 July 2018

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Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms

28 July 2018

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Kinesin-2 is a motor for late endosomes and lysosomes

28 July 2018

1 reference

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

28 July 2018

1 reference

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A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

28 July 2018

1 reference

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The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium

28 July 2018

1 reference

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A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

28 July 2018

1 reference

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Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neurons

28 July 2018

1 reference

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Redistribution of the kinesin-II subunit KAP from cilia to nuclei during the mitotic and ciliogenic cycles in sea urchin embryos

28 July 2018

1 reference

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Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body

28 July 2018

1 reference

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Hedgehog signalling in the mouse requires intraflagellar transport proteins

28 July 2018

1 reference

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28 July 2018

Intraflagellar Transport

1 reference

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Developmental roles and clinical significance of hedgehog signaling

28 July 2018

1 reference

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Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Identification of a link between the tumour suppressor APC and the kinesin superfamily

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Gli1 can rescue the in vivo function of Gli2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Stirring up development with the heterotrimeric kinesin KIF3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.

28 July 2018

1 reference

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

28 July 2018

1 reference

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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

28 July 2018

1 reference

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Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Biochemical evidence that patched is the Hedgehog receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Novel heterotrimeric kinesin-related protein purified from sea urchin eggs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Mechanistic differences in the transcriptional interpretation of local and long-range Shh morphogen signaling.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Gli proteins in development and disease

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Functional analysis of mouse kinesin motor Kif3C.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Gli proteins encode context-dependent positive and negative functions: implications for development and disease

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Characterization of the KIF3C neural kinesin-like motor from mouse

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342584

Armadillo repeats in the SpKAP115 subunit of kinesin-II

8 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25588831

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25588831

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.162552

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25588831%20AND%20SRC:MED&resulttype=core&format=json