Hedgehog signaling and the Gli code in stem cells, cancer, and metastases (Q28253856)

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Activation of the hedgehog pathway in advanced prostate cancer

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

Lessons from hereditary colorectal cancer

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002540

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Catching a Gli-mpse of Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

The Gli code: an information nexus regulating cell fate, stemness and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

A paracrine requirement for hedgehog signalling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Basal cell carcinomas in mice overexpressing sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Teratogen-mediated inhibition of target tissue response to Shh signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog signaling pathway is inactive in colorectal cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Cooperative requirement of the Gli proteins in neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog--Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Wnt signals are targets and mediators of Gli function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002540