An RNAi-based dimorphic genetic screen identified the double bromodomain protein BET-1 as a sumo-dependent attenuator of RAS-mediated signalling (Q35071050)

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English	An RNAi-based dimorphic genetic screen identified the double bromodomain protein BET-1 as a sumo-dependent attenuator of RAS-mediated signalling	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

An RNAi-based dimorphic genetic screen identified the double bromodomain protein BET-1 as a sumo-dependent attenuator of RAS-mediated signalling (English)

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Europe PubMed Central

PubMed publication ID

6 August 2017

Small ubiquitin-related modifier CELE_K12C11.2

1 reference

GOA release 2020-03-11

Bromodomain-containing protein bet-1 CELE_Y119C1B.8

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GOA release 2020-03-11

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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Fiona Gee

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Kate Fisher

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ulrike Klemstein

3

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11 June 2020

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publication date

10 December 2013

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Europe PubMed Central

PubMed publication ID

6 August 2017

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Europe PubMed Central

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11 June 2020

8

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Europe PubMed Central

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11 June 2020

12

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11 June 2020

e83659

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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Creative Commons Attribution 4.0 International

10 December 2013

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April 2022 Public Data File from Crossref

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0 references

Canonical RTK-Ras-ERK signaling and related alternative pathways

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8 July 2018

Selective inhibition of tumor oncogenes by disruption of super-enhancers

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8 July 2018

SUMO: a multifaceted modifier of chromatin structure and function

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8 July 2018

MAP kinase signalling cascades and transcriptional regulation

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8 July 2018

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.

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8 July 2018

Cytokine-induced paracrystals prolong the activity of signal transducers and activators of transcription (STAT) and provide a model for the regulation of protein solubility by small ubiquitin-like modifier (SUMO).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Chemical reprogramming of Caenorhabditis elegans germ cell fate

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Ras signaling and therapies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Identification of SUMO-interacting proteins by yeast two-hybrid analysis

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8 July 2018

The polycomb repressive complex 2 is a potential target of SUMO modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The SynMuv genes of Caenorhabditis elegans in vulval development and beyond

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Similar requirements for CDC-42 and the PAR-3/PAR-6/PKC-3 complex in diverse cell types

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

SUMO modification enhances p66-mediated transcriptional repression of the Mi-2/NuRD complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

SUMO: a history of modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The RAF proteins take centre stage

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Protein modification by SUMO

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Nuclear and unclear functions of SUMO

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Targeting RAS signalling pathways in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

1 reference

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8 July 2018

The ubiquitin system

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8 July 2018

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase

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8 July 2018

Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The genetics of Caenorhabditis elegans

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8 July 2018

Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans

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8 July 2018

A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862036

8 July 2018

The gene lin-3 encodes an inductive signal for vulval development in C. elegans

1 reference

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8 July 2018

RAS oncogenes: the first 30 years.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083659

21 January 2018

A module of negative feedback regulators defines growth factor signaling

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083659

21 January 2018

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development

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21 January 2018

Methylation and demethylation activities of a C. elegans MLL-like complex attenuate RAS signalling.

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21 January 2018

Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen.

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21 January 2018

Double bromodomain protein BET-1 and MYST HATs establish and maintain stable cell fates in C. elegans.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083659

21 January 2018

The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. elegans

1 reference

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21 January 2018

Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development

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21 January 2018

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

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21 January 2018

A Proteome-wide Approach Identifies Sumoylated Substrate Proteins in Yeast

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21 January 2018

Global Map of SUMO Function Revealed by Protein-Protein Interaction and Genetic Networks

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21 January 2018

Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response

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21 January 2018

SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24349540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SUMO engages multiple corepressors to regulate chromatin structure and transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/24349540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression markers for Caenorhabditis elegans vulval cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24349540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0083659

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

2013PLoSO...883659G

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24349540%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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