Mouse models of neurofibromatosis type I: bridging the GAP. (Q35043758)

6 August 2017

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title

Mouse models of neurofibromatosis type I: bridging the GAP. (English)

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6 August 2017

neurofibromatosis type I

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1

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6 August 2017

Alcino J Silva

2

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publication date

1 January 2003

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Trends in Molecular Medicine

6 August 2017

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6 August 2017

9

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6 August 2017

1

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6 August 2017

19-23

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Neurofibromin, a tumor suppressor in the nervous system

6 August 2017

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

NF1 tumor suppressor gene function: narrowing the GAP

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Neurofibromatosis type 1

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Mutations in the GAP-related domain impair the ability of neurofibromin to associate with microtubules.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Mouse neurofibromatosis type 1 cDNA sequence reveals high degree of conservation of both coding and non-coding mRNA segments.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

DNA sequences in the promoter region of the NF1 gene are highly conserved between human and mouse.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Mouse models of tumor development in neurofibromatosis type 1

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Mouse tumor model for neurofibromatosis type 1

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A mouse model for the learning and memory deficits associated with neurofibromatosis type I

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

1 reference

7 January 2021

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Inducible, pharmacogenetic approaches to the study of learning and memory.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A role for the Ras signalling pathway in synaptic transmission and long-term memory

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The MAPK cascade is required for mammalian associative learning.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Place navigation impaired in rats with hippocampal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Loss of recent memory after bilateral hippocampal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Neuroanatomy of memory

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Regulation of long-term potentiation by H-Ras through NMDA receptor phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Multiprotein complex signaling and the plasticity problem.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Impairment of inhibitory synaptic transmission in mice lacking synapsin I.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Muscimol injections in the medial septum impair spatial learning.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

A model of hippocampal memory encoding and retrieval: GABAergic control of synaptic plasticity.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

Oscillatory Coupling of Hippocampal Pyramidal Cells and Interneurons in the Behaving Rat

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

The dorsal hippocampus is essential for context discrimination but not for contextual conditioning.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2900008-4

7 January 2021

10.1016/S1471-4914(02)00008-4

Identifiers

DOI

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6 August 2017

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PubMed ID

12524206