Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways (Q34965317)

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English	Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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author name string

Makoto Tsuda

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Emika Toyomitsu

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Miho Kometani

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Hidetoshi Tozaki-Saitoh

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Kazuhide Inoue

5

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Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

27 February 2009

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Europe PubMed Central

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5 August 2017

Journal of Cellular and Molecular Medicine

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Europe PubMed Central

PubMed publication ID

5 August 2017

13

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Europe PubMed Central

PubMed publication ID

5 August 2017

9B

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

3251-3259

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Transcriptional and translational regulation of TGF-beta production in response to apoptotic cells

1 reference

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Purinergic signalling and disorders of the central nervous system

1 reference

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Transcriptional control of human p53-regulated genes

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

1 reference

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Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury

1 reference

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Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination

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Control of chronic pain by the ubiquitin proteasome system in the spinal cord.

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The P2Y12 receptor regulates microglial activation by extracellular nucleotides

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P2X receptors as cell-surface ATP sensors in health and disease

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Purinergic signalling in neuron-glia interactions

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Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages

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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

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The function of microglia through purinergic receptors: neuropathic pain and cytokine release

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Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells

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Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation

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ATP mediates rapid microglial response to local brain injury in vivo

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Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt.

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Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

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The interplay between Src and integrins in normal and tumor biology

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Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

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Translational regulatory mechanisms in persistent forms of synaptic plasticity

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Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

Expression of P2X4 receptor in rat C6 glioma by tumor-associated macrophages and activated microglia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

Multisite phosphorylation provides sophisticated regulation of transcription factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

Microglial activation by purines and pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

Microglia as neuroprotective, immunocompetent cells of the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

8 July 2018

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

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8 July 2018

Live or let die: the cell's response to p53

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8 July 2018

Sensing the environment: a historical perspective on integrin signal transduction

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8 July 2018

The heparin-binding domain and V region of fibronectin regulate apoptosis by suppression of p53 and c-myc in human primary cells

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8 July 2018

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

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8 July 2018

Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5

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Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

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TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

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8 July 2018

Integrin signaling

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8 July 2018

The role of microglia and macrophages in the pathophysiology of the CNS.

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8 July 2018

Reactive microgliosis

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8 July 2018

eIF4E activity is regulated at multiple levels

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Translation initiation factor 4E.

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8 July 2018

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

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Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

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Microglia: a sensor for pathological events in the CNS

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TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity

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21 January 2018

Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

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Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia

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p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

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Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA.

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Spinal cord injury induces early and persistent lesional P2X4 receptor expression

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Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain

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Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516482

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Characterization of brain microglia and the biological significance in the central nervous system

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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

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Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis

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https://pubmed.ncbi.nlm.nih.gov/19298529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of elastase as a secretory protease from cultured rat microglia

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https://pubmed.ncbi.nlm.nih.gov/19298529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19298529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19298529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1111/J.1582-4934.2009.00719.X

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Europe PubMed Central

PubMed publication ID

5 August 2017

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https://api.fatcat.wiki/v0/release/bjzuwal44fgpbgg26qxaymk2vi

24 November 2022

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Europe PubMed Central

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5 August 2017

PubMed publication ID

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Europe PubMed Central

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5 August 2017

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