p300/MDM2 complexes participate in MDM2-mediated p53 degradation (Q28288274)

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6 December 2019

title

p300/MDM2 complexes participate in MDM2-mediated p53 degradation (English)

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6 December 2019

8

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6 December 2019

author name string

S R Grossman

1

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6 December 2019

M Perez

2

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6 December 2019

A L Kung

3

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6 December 2019

M Joseph

4

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6 December 2019

C Mansur

5

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6 December 2019

Z X Xiao

6

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6 December 2019

S Kumar

7

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6 December 2019

D M Livingston

9

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6 December 2019

publication date

1 October 1998

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6 December 2019

language of work or name

0 references

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6 December 2019

volume

2

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6 December 2019

issue

4

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6 December 2019

page(s)

405-415

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An essential role for p300/CBP in the cellular response to hypoxia

6 December 2019

cites work

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7 January 2021

The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300.

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7 January 2021

Recruitment of p300/CBP in p53-dependent signal pathways

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Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

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Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

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High-efficiency transformation of mammalian cells by plasmid DNA

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Mapping of the p53 and mdm-2 Interaction Domains

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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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Association of p300 and CBP with simian virus 40 large T antigen

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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

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7 January 2021

Synergistic activation of transcription by CBP and p53

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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Roles of ubiquitin-mediated proteolysis in cell cycle control

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

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7 January 2021

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

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7 January 2021

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

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7 January 2021

p53: puzzle and paradigm

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Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

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Regulation of p53 stability by Mdm2

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Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Binding and modulation of p53 by p300/CBP coactivators

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7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

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7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

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7 January 2021

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

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7 January 2021

The transcriptional coactivators p300 and CBP are histone acetyltransferases

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

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7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

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7 January 2021

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

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7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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7 January 2021

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