ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells (Q34854378)

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English	ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells (English)

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Europe PubMed Central

4 August 2017

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phosphorylation

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based on heuristic

inferred from title

author name string

Ynes A Helou

1

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Europe PubMed Central

4 August 2017

Vinh Nguyen

2

1 reference

Europe PubMed Central

4 August 2017

Samantha P Beik

3

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Europe PubMed Central

4 August 2017

Arthur R Salomon

4

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Europe PubMed Central

4 August 2017

language of work or name

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publication date

17 July 2013

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Europe PubMed Central

4 August 2017

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Europe PubMed Central

4 August 2017

8

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Europe PubMed Central

4 August 2017

e69641

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Europe PubMed Central

4 August 2017

7

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Europe PubMed Central

4 August 2017

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Creative Commons Attribution 4.0 International

17 July 2013

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April 2022 Public Data File from Crossref

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TCR activation kinetics and feedback regulation in primary human T cells

1 reference

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KEGG for integration and interpretation of large-scale molecular data sets

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8 July 2018

Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

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8 July 2018

T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component

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8 July 2018

Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity

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HTAPP: high-throughput autonomous proteomic pipeline

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8 July 2018

Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response

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PeptideDepot: flexible relational database for visual analysis of quantitative proteomic data and integration of existing protein information

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8 July 2018

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions

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Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways

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8 July 2018

A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation

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Integrated platform for manual and high-throughput statistical validation of tandem mass spectra

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8 July 2018

The structure, regulation, and function of ZAP-70.

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8 July 2018

Tailoring T-cell receptor signals by proximal negative feedback mechanisms

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8 July 2018

A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Structural basis for the inhibition of tyrosine kinase activity of ZAP-70

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8 July 2018

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

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8 July 2018

Regulation of T-cell activation by the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

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A probability-based approach for high-throughput protein phosphorylation analysis and site localization

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8 July 2018

Identification of substrates of human protein-tyrosine phosphatase PTPN22

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8 July 2018

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

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8 July 2018

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

1 reference

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8 July 2018

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Jurkat T cells and development of the T-cell receptor signalling paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Lck Dephosphorylation at Tyr-394 and Inhibition of T Cell Antigen Receptor Signaling by Yersinia Phosphatase YopH

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Statistical significance for genomewide studies

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8 July 2018

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

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8 July 2018

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

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8 July 2018

SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Protein tyrosine phosphorylation in T cell signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714263

8 July 2018

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

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8 July 2018

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

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8 July 2018

Probability-based protein identification by searching sequence databases using mass spectrometry data

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8 July 2018

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8 July 2018

Cutting edge: SLP-76 cooperativity with FYB/FYN-T in the Up-regulation of TCR-driven IL-2 transcription requires SLP-76 binding to FYB at Tyr595 and Tyr651

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8 July 2018

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

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8 July 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy.

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Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

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Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK.

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Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function

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8 July 2018

Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck

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8 July 2018

Phosphorylation of serine 59 of p56lck in activated T cells.

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8 July 2018

Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function

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8 July 2018

Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain

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8 July 2018

Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.

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8 July 2018

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

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8 July 2018

The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation.

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8 July 2018

Do CD4 and CD8 control T-cell activation via a specific tyrosine protein kinase?

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8 July 2018

Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation

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8 July 2018

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

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8 July 2018

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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8 July 2018

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069641

21 January 2018

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

1 reference

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21 January 2018

Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells

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21 January 2018

A direct approach to false discovery rates

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21 January 2018

The positive false discovery rate: a Bayesian interpretation and the q -value

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21 January 2018

Regulation of the Lck SH2 domain by tyrosine phosphorylation

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21 January 2018

Tuning the immune system: competing positive and negative feedback loops

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https://pubmed.ncbi.nlm.nih.gov/23874979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling

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https://pubmed.ncbi.nlm.nih.gov/23874979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0069641

1 reference

Europe PubMed Central

4 August 2017

2013PLoSO...869641H

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1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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