Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity (Q28249985)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9312162%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity (English)

1 reference

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6 November 2019

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3

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6 November 2019

author name string

S D Heyeck

series ordinal

1

1 reference

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6 November 2019

H M Wilcox

series ordinal

2

1 reference

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6 November 2019

L J Berg

series ordinal

4

1 reference

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6 November 2019

language of work or name

English

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publication date

1 October 1997

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Journal of Biological Chemistry

6 November 2019

published in

1 reference

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6 November 2019

volume

272

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6 November 2019

page(s)

25401-25408

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6 November 2019

issue

40

1 reference

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Complex complexes: signaling at the TCR.

6 November 2019

cites work

1 reference

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itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2

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A novel human tyrosine kinase gene inducible in T cells by interleukin 2

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The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

21 January 2018

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Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

21 January 2018

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Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells

21 January 2018

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Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking

21 January 2018

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Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement

21 January 2018

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

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Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

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Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell line

21 January 2018

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CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

21 January 2018

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p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

21 January 2018

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Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.

21 January 2018

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Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src

21 January 2018

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Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation

21 January 2018

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Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

21 January 2018

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Csk suppression of Src involves movement of Csk to sites of Src activity

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Active and inactive protein kinases: structural basis for regulation

21 January 2018

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CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK.

21 January 2018

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

21 January 2018

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Regulation of Btk function by a major autophosphorylation site within the SH3 domain

21 January 2018

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

21 January 2018

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Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase

21 January 2018

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Regulation of Btk by Src family tyrosine kinases

21 January 2018

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Regulatory intramolecular association in a tyrosine kinase of the Tec family

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A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

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