Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue (Q34718662)

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English	Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue	scientific article

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24 January 2020

Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue (English)

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Greg M Kowalski

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Hayley T Nicholls

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David J Kennedy

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Steve Risis

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Lee A Zaffino

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Nadine Watson

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Peter Kanellakis

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Matthew J Watt

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Alex Bobik

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Arend Bonen

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Maria Febbraio

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Graeme I Lancaster

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Mark A Febbraio

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4 March 2011

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1100-1110

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

27 August 2021

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A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling

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JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction

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7 July 2018

DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.

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7 July 2018

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

1 reference

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7 July 2018

Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis

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7 July 2018

CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior

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7 July 2018

The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation

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7 July 2018

CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima

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7 July 2018

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

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7 July 2018

Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

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7 July 2018

A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity

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7 July 2018

Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice

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7 July 2018

CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice

1 reference

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7 July 2018

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis

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7 July 2018

Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II

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7 July 2018

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

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7 July 2018

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

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7 July 2018

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

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7 July 2018

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

1 reference

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7 July 2018

CD36: implications in cardiovascular disease

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7 July 2018

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

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7 July 2018

Inflammation and metabolic disorders

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7 July 2018

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

1 reference

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7 July 2018

TLR4 links innate immunity and fatty acid-induced insulin resistance

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7 July 2018

Ceramides in insulin resistance and lipotoxicity

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7 July 2018

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

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7 July 2018

Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle

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7 July 2018

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

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7 July 2018

CD36 is a sensor of diacylglycerides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064084

7 July 2018

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

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7 July 2018

Beta-adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling.

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Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

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Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake

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Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

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Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain

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Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance

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26 October 2018

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

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26 October 2018

Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro

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26 October 2018

CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice

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26 October 2018

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

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26 October 2018

CD36 deficiency associated with insulin resistance.

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26 October 2018

A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

1 reference

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26 October 2018

Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21378177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte death, adipose tissue remodeling, and obesity complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/21378177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21378177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21378177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB10-1353

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24 January 2020

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Europe PubMed Central

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24 January 2020

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