Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment (Q34602948)

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English	Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment (English)

1 reference

Europe PubMed Central

3 August 2017

1 reference

based on heuristic

inferred from title

multicellularity

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Joakim E. Swedberg

object named as

Joakim E Swedberg

4

0 references

Jonathan Harris

object named as

Jonathan M Harris

8

0 references

object named as

Glen M Boyle

5

0 references

Michael A McGuckin

object named as

Michael A McGuckin

7

0 references

Peter G. Parsons

object named as

Peter G Parsons

6

0 references

Judith Clements

object named as

Judith A Clements

9

0 references

author name string

Ying Dong

1

1 reference

Europe PubMed Central

3 August 2017

Carson Stephens

2

1 reference

Europe PubMed Central

3 August 2017

Carina Walpole

3

1 reference

Europe PubMed Central

3 August 2017

language of work or name

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publication date

25 February 2013

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Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

8

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Europe PubMed Central

3 August 2017

2

1 reference

Europe PubMed Central

3 August 2017

e57056

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

25 February 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis

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7 July 2018

Ovarian cancer spheroids use myosin-generated force to clear the mesothelium

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7 July 2018

Characterization of kallikrein-related peptidase 4 glycosylations

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7 July 2018

Cancer statistics, 2012

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7 July 2018

Kallikreins 5, 6 and 10 differentially alter pathophysiology and overall survival in an ovarian cancer xenograft model

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7 July 2018

Practical considerations in ovarian cancer chemotherapy

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New determinates of disease progression and outcome in metastatic ovarian carcinoma

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7 July 2018

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma

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Functional proteomics of kallikrein-related peptidases in ovarian cancer ascites fluid

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Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus

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Functional roles of human kallikrein-related peptidases

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Microenvironmental regulation of ovarian cancer metastasis

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7 July 2018

Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression

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7 July 2018

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

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7 July 2018

The biology of ovarian cancer: new opportunities for translation

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7 July 2018

Spheroid-based drug screen: considerations and practical approach

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7 July 2018

The urokinase plasminogen activator system: a target for anti-cancer therapy.

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7 July 2018

Multicellular spheroids in ovarian cancer metastases: Biology and pathology.

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7 July 2018

Mining the ovarian cancer ascites proteome for potential ovarian cancer biomarkers

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Functions of KLK4 and MMP-20 in dental enamel formation

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Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains

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Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression

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7 July 2018

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression

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7 July 2018

Drug penetration in solid tumours

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Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms.

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7 July 2018

Ascites induces modulation of alpha6beta1 integrin and urokinase plasminogen activator receptor expression and associated functions in ovarian carcinoma.

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7 July 2018

The emerging roles of human tissue kallikreins in cancer

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7 July 2018

The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers

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Human tissue kallikreins: physiologic roles and applications in cancer.

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Inhibition of the tumor-associated urokinase-type plasminogen activation system: effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and in vivo

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7 July 2018

Differential splicing of KLK5 and KLK7 in epithelial ovarian cancer produces novel variants with potential as cancer biomarkers

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7 July 2018

Parallel overexpression of seven kallikrein genes in ovarian cancer.

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7 July 2018

Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase

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7 July 2018

Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids

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7 July 2018

Higher human kallikrein gene 4 (KLK4) expression indicates poor prognosis of ovarian cancer patients.

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Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas

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AlphaV- and beta1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients

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Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer.

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Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype.

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Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha.

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Distribution of 15 human kallikreins in tissues and biological fluids.

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Impact of expression differences of kallikrein-related peptidases and of uPA and PAI-1 between primary tumor and omentum metastasis in advanced ovarian cancer

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Ovarian cancer specific kallikrein profile in effusions

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E-cadherin and alpha-, beta-, and gamma-catenin protein expression is up-regulated in ovarian carcinoma cells in serous effusions

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stage at diagnosis of ovarian cancer in the United States, 1992-1997

1 reference

https://pubmed.ncbi.nlm.nih.gov/23451143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23451143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0057056

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...857056D

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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