Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins (Q34580652)

3 August 2017

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title

Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins (English)

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3 August 2017

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Shiro Suetsugu

1

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PubMed ID

11921168

3 August 2017

Hiroaki Miki

series ordinal

2

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PubMed ID

11921168

3 August 2017

Tadaomi Takenawa

series ordinal

3

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3 August 2017

1 March 2002

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3 August 2017

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3 August 2017

51

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3 August 2017

3

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3 August 2017

113-122

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The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments

3 August 2017

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

21 January 2018

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Gelsolin is a downstream effector of rac for fibroblast motility

21 January 2018

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21 January 2018

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Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

21 January 2018

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Listeria protein ActA mimics WASp family proteins: it activates filament barbed end branching by Arp2/3 complex

21 January 2018

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Motility of ActA protein-coated microspheres driven by actin polymerization

21 January 2018

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Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

21 January 2018

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GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex

21 January 2018

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Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion

21 January 2018

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How is actin polymerization nucleated in vivo?

21 January 2018

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Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

21 January 2018

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A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

21 January 2018

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Two pathways through Cdc42 couple the N-formyl receptor to actin nucleation in permeabilized human neutrophils

21 January 2018

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Activation of the Arp2/3 complex by the actin filament binding protein Abp1p

21 January 2018

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Functions of gelsolin: motility, signaling, apoptosis, cancer

21 January 2018

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Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

21 January 2018

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Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

21 January 2018

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Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose

21 January 2018

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21 January 2018

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Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

21 January 2018

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

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IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

21 January 2018

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Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba

21 January 2018

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The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

21 January 2018

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How profilin promotes actin filament assembly in the presence of thymosin beta 4.

21 January 2018

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The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins

21 January 2018

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Mechanism of actin-based motility.

21 January 2018

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Molecular mechanisms controlling actin filament dynamics in nonmuscle cells

21 January 2018

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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

21 January 2018

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

21 January 2018

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

21 January 2018

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Arp2/3 complex-independent actin regulatory function of WAVE.

21 January 2018

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Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides

21 January 2018

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The essential role of profilin in the assembly of actin for microspike formation

21 January 2018

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Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

21 January 2018

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Identification of another actin-related protein (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin polymerization induced by the Arp2/3 complex activating (VCA) domain of N-WASP.

21 January 2018

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Requirement of the basic region of N-WASP/WAVE2 for actin-based motility.

21 January 2018

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Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri

21 January 2018

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Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP.

21 January 2018

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Activation of Arp2/3 complex-mediated actin polymerization by cortactin

21 January 2018

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Structure of Arp2/3 complex in its activated state and in actin filament branch junctions

21 January 2018

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Actin dynamics: assembly and disassembly of actin networks

21 January 2018

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Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

21 January 2018

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Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes

21 January 2018

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Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.

21 January 2018

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Profilin enhances Cdc42-induced nucleation of actin polymerization

21 January 2018

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Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

21 January 2018

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Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension

21 January 2018

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The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension

21 January 2018

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Mammalian Abp1, a Signal-Responsive F-Actin–Binding Protein, Links the Actin Cytoskeleton to Endocytosis via the Gtpase Dynamin

21 January 2018

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Dendritic organization of actin comet tails

21 January 2018

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Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

21 January 2018

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7 January 2021

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

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7 January 2021

Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization

1 reference

7 January 2021

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

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7 January 2021

Identifiers

DOI

10.1002/CM.10020

1 reference

3 August 2017

1 reference

PubMed ID

11921168