SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development (Q24311769)

DOI

10.1083/JCB.142.5.1325

https://api.crossref.org/works/10.1083/JCB.142.5.1325

8 January 2025

1 reference

GOA release 2020-03-11

actin cytoskeleton organization

1 reference

GOA release 2020-03-11

author name string

J. E. Bear

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

8 January 2025

J. F. Rawls

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

8 January 2025

C. L. Saxe

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

http://jcb.rupress.org/content/142/5/1325.full.pdf

8 January 2025

publication date

7 September 1998

0 references

language of work or name

English

0 references

work available at URL

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

https://europepmc.org/articles/PMC2149354

8 January 2025

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

https://europepmc.org/articles/PMC2149354?pdf=render

8 January 2025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9732292

https://rupress.org/jcb/article-pdf/142/5/1325/1847591/9805041.pdf

8 January 2025

1 reference

10.1083/JCB.142.5.1325

https://api.crossref.org/works/10.1083/JCB.142.5.1325

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

8 January 2025

published in

Journal of Cell Biology

0 references

volume

142

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issue

5

0 references

page(s)

1325-35

0 references

cites work

1 reference

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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

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FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

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Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis

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Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

19 March 2017

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Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

19 March 2017

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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

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The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins

19 March 2017

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Actin-binding Verprolin Is a Polarity Development Protein Required for the Morphogenesis and Function of the Yeast Actin Cytoskeleton

19 March 2017

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Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae

19 March 2017

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Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton

19 March 2017

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Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

19 March 2017

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Saccharomyces cerevisiae mutants unresponsive to alpha-factor pheromone: alpha-factor binding and extragenic suppression

19 March 2017

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Signaling Through Scaffold, Anchoring, and Adaptor Proteins

19 March 2017

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The WW Domain of Neural Protein FE65 Interacts with Proline-rich Motifs in Mena, the Mammalian Homolog of DrosophilaEnabled

19 March 2017

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Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity

19 March 2017

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Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains

19 March 2017

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

19 March 2017

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EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

19 March 2017

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Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics

19 March 2017

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N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

19 March 2017

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cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin

7 April 2017

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Developmental signal transduction pathways uncovered by genetic suppressors

27 September 2017

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Signaling through chemoattractant receptors in Dictyostelium

27 September 2017

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Molecular genetics of signal transduction in Dictyostelium

27 September 2017

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Disease mechanism: unravelling Wiskott-Aldrich syndrome

27 September 2017

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Signal transduction and actin filament organization

27 September 2017

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A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis

27 September 2017

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Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

27 September 2017

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CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum

27 September 2017

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How profilin promotes actin filament assembly in the presence of thymosin beta 4.

27 September 2017

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G protein-linked signaling pathways control the developmental program of Dictyostelium

27 September 2017

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A proline-rich protein, verprolin, involved in cytoskeletal organization and cellular growth in the yeast Saccharomyces cerevisiae

27 September 2017

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27 September 2017

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Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae

27 September 2017

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Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development

27 September 2017

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A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

27 September 2017

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Molecular insights into eukaryotic chemotaxis

27 September 2017

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T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome

27 September 2017

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Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA.

27 September 2017

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The function of inositol high polyphosphate binding proteins

27 September 2017

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The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development.

30 May 2018

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The cAMP receptor subtype cAR2 is restricted to a subset of prestalk cells during Dictyostelium development and displays unexpected DIF-1 responsiveness

30 May 2018

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The regulation of Dictyostelium development by transmembrane signalling

30 May 2018

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Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination

30 May 2018

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Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum.

30 May 2018

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A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

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Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

30 May 2018

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Analysis of a spatially regulated phosphotyrosine phosphatase identifies tyrosine phosphorylation as a key regulatory pathway in Dictyostelium

30 May 2018

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Changes in the association of actin-binding proteins with the actin cytoskeleton during chemotactic stimulation of Dictyostelium discoideum

30 May 2018

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Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development

21 January 2018

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Tyrosine Phosphorylation of Actin in Dictyostelium Associated with Cell-Shape Changes

21 January 2018

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Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants

21 January 2018

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The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets

21 January 2018

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12 December 2020

Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome

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Agar-overlay immunofluorescence: high-resolution studies of cytoskeletal components and their changes during chemotaxis

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ABM-1 and ABM-2 homology sequences: consensus docking sites for actin-based motility defined by oligoproline regions in Listeria ActA surface protein and human VASP

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Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation

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Direct Binding of the Verprolin-Homology Domain in N-WASP to Actin Is Essential for Cytoskeletal Reorganization

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Simultaneous visualization of G- and F-actin in endothelial cells

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Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker

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12 December 2020