The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling (Q34500164)

2 August 2017

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling (English)

1 reference

2 August 2017

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protein ubiquitination

1 reference

Madison Bolger-Munro

7

0 references

Catherine H Regnier

Catherine H Régnier

14

0 references

Shan-Yu Fung

Shan-Yu Fung

2

0 references

John J. Priatel

John J Priatel

9

0 references

Michael R. Gold

Michael R Gold

12

0 references

Stuart E Turvey

Stuart E Turvey

15

0 references

Christopher Overall

16

Christopher M Overall

1 reference

2 August 2017

8

Joshua M Scurll

1 reference

2 August 2017

Theo Klein

1

1 reference

2 August 2017

Florian Renner

3

1 reference

2 August 2017

Michael A Blank

4

1 reference

2 August 2017

Antoine Dufour

5

1 reference

2 August 2017

Sohyeong Kang

6

1 reference

2 August 2017

Patrick Schweigler

10

1 reference

2 August 2017

Samu Melkko

11

1 reference

2 August 2017

Rosa I Viner

13

1 reference

2 August 2017

language of work or name

English

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publication date

3 November 2015

1 reference

2 August 2017

Nature Communications

1 reference

2 August 2017

6

1 reference

2 August 2017

8777

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

start time

3 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms9777

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cites work

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Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

7 July 2018

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Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.

7 July 2018

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Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation

7 July 2018

1 reference

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Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity

7 July 2018

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Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.

7 July 2018

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Targeting B-cell lymphomas with inhibitors of the MALT1 paracaspase

7 July 2018

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Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

7 July 2018

1 reference

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MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes

7 July 2018

1 reference

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The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency

7 July 2018

1 reference

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MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.

7 July 2018

1 reference

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Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

7 July 2018

1 reference

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A catalytic-independent role for the LUBAC in NF-κB activation upon antigen receptor engagement and in lymphoma cells.

7 July 2018

1 reference

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Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms

7 July 2018

1 reference

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BoxPlotR: a web tool for generation of box plots

7 July 2018

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Mechanism Underlying I B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Innate immune control of EBV-infected B cells by invariant natural killer T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Linear ubiquitination: a newly discovered regulator of cell signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Structural determinants of MALT1 protease activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Mechanism and specificity of the human paracaspase MALT1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Inflammation meets cancer, with NF-κB as the matchmaker

7 July 2018

1 reference

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From MALT lymphoma to the CBM signalosome: three decades of discovery

7 July 2018

1 reference

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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

7 July 2018

1 reference

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SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

7 July 2018

1 reference

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Linear ubiquitination prevents inflammation and regulates immune signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

MALT lymphoma: many roads lead to nuclear factor-κb activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

7 July 2018

NF-κB in immunobiology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Microsignalosomes: spatially resolved receptor signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

The who, how and where of antigen presentation to B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

BioVenn - a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

A ubiquitin ligase complex assembles linear polyubiquitin chains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Lessons learned from molecular defects in nuclear factor kappaB dependent signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

The MAGUK family protein CARD11 is essential for lymphocyte activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Transcriptional activity of RBCK1 protein (RBCC protein interacting with PKC 1): requirement of RING-finger and B-Box motifs and regulation by protein kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Release of infectious Epstein-Barr virus by transformed marmoset leukocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4659944

Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

Combined immunodeficiency associated with homozygous MALT1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS9777

21 January 2018

Identifiers

DOI

10.1038/NCOMMS9777

1 reference

Dimensions Publication ID

2 August 2017

0 references

0 references

1 reference

2 August 2017

1 reference